Search for dissertations about: "Metabolic stability"

Showing result 1 - 5 of 90 swedish dissertations containing the words Metabolic stability.

  2. 1. Gene Regulatory Networks: Dynamics and Stability

    Author : Carl Troein; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; systems; control; Datalogi; numerisk analys; system; kontroll; Computer science; numerical analysis; Fysik; biomathematics biometrics; Bioinformatik; medicinsk informatik; biomatematik; Physics; medical informatics; transcriptional regulation; gene regulatory networks; Bioinformatics; signaling pathway profiling; stem cell regulation; metabolic pathway; fitness; nested canalyzing rules; Kauffman networks; random Boolean networks; Fysicumarkivet:2007:Troein;

    Abstract : Life as we know it is based on cells that use proteins and RNA to carry out metabolism, self-replication, and other essential tasks. The genes that code for these molecules are encoded in DNA, and through the processes of transcription and translation the cell expresses its genes. READ MORE

  4. 2. Systems-level characterization of probiotic bifidobacteria - Towards rational optimization of industrial production

    Author : Marie Schöpping; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; genome-scale metabolic modeling; stability; robustness; industrial manufacturing; bifidobacteria; stress-associated genes; probiotics; nutritional requirement; interspecies variations;

    Abstract : Probiotic Bifidobacterium strains contribute to a healthy gut microbiota of their hosts. Increasing public awareness of this positive effect has resulted in a growing demand for these microorganisms. READ MORE

  5. 3. Structure, function and metabolic stability of antisense RNAs

    Author : Fredrik Söderbom; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Mikrobiologi; Microbiology; Mikrobiologi; mikrobiologi; Microbiology;

    Abstract : Antisense RNAs usually are small, highly structured, unstable RNAs that control a varietyof different biological processes. They exert their effect by binding to complementarytarget RNAs and thereby inhibit their functions. READ MORE

  6. 4. Cytokines in Metabolic Functions

    Author : Anna Benrick; Göteborgs universitet; []
    Keywords : IL-1; IL-6; LIF; obesity; fat mass; energy expenditure; hypothalamus; gp130 SNP; myocardial infarction;

    Abstract : During infections, circulating cytokines are largely produced by immune cells. In healthy obese individuals, large parts of these circulating cytokines are produced in adipose tissue, for instance by macrophages that have accumulated there. READ MORE

  7. 5. Ligands of the Angiotensin II Type 2 Receptor : Exploring structure and function of the AT2R ligand C38

    Author : Rebecka Isaksson; Mats Larhed; Annette Bayer; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiotensin II type 2 receptor; AT2R antagonists; sulfonyl carbamates; bicyclic amides; metabolic stability; functional activity assay; pharmacological profile; medicinal chemistry; structure-activity relationship; Medicinal Chemistry; Läkemedelskemi;

    Abstract : The renin-angiotensin-aldosterone-system (RAAS) control blood-pressure regulation, exerted by the main effector peptide angiotensin II (AngII) binding the angiotensin II type 1 receptor (AT1R). While hypertension is the most known disease caused by over-activity in RAAS, several proteins in the system exhibit protective functions. READ MORE