Search for dissertations about: "Method development ion chromatography"

Showing result 1 - 5 of 25 swedish dissertations containing the words Method development ion chromatography.

  1. 1. High Rate Electron Capture Dissociation Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Youri Tsybin; Uppsala universitet.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physics; mass spectrometry; Fourier transform ion cyclotron resonance; peptides and proteins; ion-electron interaction; electron capture dissociation; infrared multiphoton dissociation; liquid chromatography; capillary electrophoresis; Fysik; NATURAL SCIENCES Physics; NATURVETENSKAP Fysik;

    Abstract : Advances in science and technology during the past decade have greatly enhanced the level of the structural investigation of macromolecules – peptides and proteins. Biological mass spectrometry has become one of the most precise and sensitive techniques in peptide and protein analysis. READ MORE

  2. 2. Method Development in Quantitative and Structural Proteomics using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Charlotte Hagman; Uppsala universitet.; [2005]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Cerebrospinal Fluid; Electrospray Ionization; Fourier Transform Ion Cyclotron Resonance Mass Spectrometry; Global Markers; High Performance Liquid Chromatography; Gas-Phase Exchange; Hydrogen Deuterium Exchange; Plasma; Protoemics; Quantification; Structural Elucidation; Bioteknik; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Abstract : In this thesis, methods for studying different aspects of proteomics were developed with Fourier Transform Ion Cyclotron Resonance, (FTICR), mass spectrometry. The FTICR technique provides ultra-high mass resolving power, mass accuracy at sub ppm level and sensitivity in the attomole region. READ MORE

  3. 3. Liquid Chromatography Coupled to Mass Spectrometry Implementation of Chemometric Optimization and Selected Applications

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : My Moberg; Uppsala universitet.; [2006]
    Keywords : Analytical chemistry; liquid chromatography; mass spectrometry; tandem mass spectrometry; electrospray ionization; inductively coupled plasma; chemometrics; optimization; multivariate data analysis; design of experiments; response surface model; siderophore; azathioprine; peptide; Analytisk kemi;

    Abstract : Liquid chromatography (LC) coupled to mass spectrometry (MS) offers highly selective and sensitive analysis of a wide variety of compounds. However, the use of hyphenated experimental set-ups implies that many parameters may have an effect on the studied response. READ MORE

  4. 4. Improved analytical methods for perfluoroalkyl acids (PFAAs) and their precursors – a focus on human dietary exposure

    University dissertation from Stockholm : Department of Applied Environmental Science (ITM), Stockholm University

    Author : Shahid Ullah; Stockholms universitet.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental Science; PFASs; PFAAs; PFOA; PFOS; Precursor; FOSA; PAPs; Method development; LC-MS; SPE; Dietary sample; Drinking water; Human exposure; Applied Environmental Science; tillämpad miljövetenskap;

    Abstract : Per- and polyfluoroalkyl substances are a large group of global environmental contaminants. They can be divided into two sub-groups, 1) perfluoroalkyl acids (PFAAs) and 2) so called precursors, i.e. compounds that can potentially be transformed to form PFAAs. READ MORE

  5. 5. Identification and Characterization of Peptides and Proteins using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Magnus Palmblad; Uppsala universitet.; [2002]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Materials science; Peptide; protein; peptide mass fingerprinting; identification; sequencing; protein structure; non-covalent interaction; modification; electrospray ionization; liquid chromatography; capillary electrophoresis; electron capture dissociation; Fourier transform ion cyclotron resonance mass spectrometry; cerebrospinal fluid; amyloid β-peptide; Alzheimer’s disease.; Materialvetenskap; TECHNOLOGY Materials science; TEKNIKVETENSKAP Teknisk materialvetenskap; Molecular Biotechnology; Molekylär bioteknik;

    Abstract : Mass spectrometry has in recent years been established as the standard method for protein identification and characterization in proteomics with excellent intrinsic sensitivity and specificity. Fourier transform ion cyclotron resonance is the mass spectrometric technique that provides the highest resolving power and mass accuracy, increasing the amount of information that can be obtained from complex samples. READ MORE