Search for dissertations about: "Microneedles"

Found 5 swedish dissertations containing the word Microneedles.

2. 1. Ceramic Materials for Administration of Potent Drugs

   Author : Bing Cai; Susanne Bredenberg; Håkan Engqvist; Wei Xia; Miguel Manzano García; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Tamper-resistance; Oral formulation; Transdermal formulation; Biomaterials; Microneedles;

   Abstract : This thesis aimed to investigate and document the potential of applying ceramics in two specific drug delivery applications: tamper-resistant opioid formulations and transdermal enhancement protrusions.Geopolymers were developed into the matrix for a tamper-resistant formulation, aiming to protect drug substances from non-medical abuse. READ MORE

4. 2. Integrated microsystems for continuous glucose monitoring, interstitial fluid sampling and digital microfluidics

   Author : Federico Ribet; Niclas Roxhed; Göran Stemme; Boris Stoeber; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microelectromechanical systems MEMS ; biosensors; biomedical devices; continuous glucose monitoring CGM ; glucose sensors; microneedles; interstitial fluid sampling; minimally-invasive technologies; electrochemical sensors; heterogeneous integration; wire bonding; magnetic assembly; electrowetting-on-dielectric EWOD ; digital microfluidics; ionic liquids; gas sensors; optical switches; laser shutters.; Electrical Engineering; Elektro- och systemteknik;

   Abstract : Interdisciplinary research between medicine and microsystem engineering creates new possibilities to improve the quality of life of patients or to further enhance the performance of already existing devices. In particular, microsystems show great potential for the realization of biosensors and sampling devices to monitor bioanalytes with minimal patient discomfort. READ MORE

5. 3. Flexible and Stretchable Biointerfacing for Healthcare Diagnostics

   Author : Mina Rajabi; Niclas Roxhed; Pelle Rangsten; KTH; []
   Keywords : Wearable biointerfacing sensor; flexible and stretchable microneedles patch; wearable microneedles device; health and fitness monitoring; minimally invasive ICP monitoring; bioelectronics; Electrical Engineering; Elektro- och systemteknik;

   Abstract : Flexible and stretchable wearable biomedical devices provide a platform for continues long-term monitoring of biological signals during neutral body movements thus enabling early intervention and diagnostics of various diseases. This thesis evaluates novel flexible and stretchable bio interfacing medical devices based on microneedle patches and split ring resonator for healthcare diagnostics. READ MORE

6. 4. A Fully Integrated Microneedle-based Transdermal Drug Delivery System

   Author : Niclas Roxhed; Göran Stemme; Mark G. Allen; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microneedle; Transdermal; Intradermal; Drug delivery; DRIE; MEMS; Microsystem; Medical technology; Medicinsk teknik;

   Abstract : Patch-based transdermal drug delivery offers a convenient way to administer drugs without the drawbacks of standard hypodermic injections relating to issues such as patient acceptability and injection safety. However, conventional transdermal drug delivery is limited to therapeutics where the drug can diffuse across the skin barrier. READ MORE

7. 5. Novel Microfluidic Devices Based on a Thermally Responsive PDMS Composite

   Author : Björn Samel; Göran Stemme; Jörg Kutter; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEMS; microsystem technology; micro total analysis system; lab-on-a-chip; microfluidics; composite actuator; expandable microspheres; PDMS; poly dimethylsiloxane; disposable; wafer bonding; adhesive bonding; PDMS bonding; adhesive PDMS bonding; selective PDMS bonding; microcontact printing; Electrical engineering; Elektroteknik;

   Abstract : The field of micro total analysis systems (μTAS) aims at developments toward miniaturized and fully integrated lab-on-a-chip systems for applications, such as drug screening, drug delivery, cellular assays, protein analysis, genomic analysis and handheld point-of-care diagnostics. Such systems offer to dramatically reduce liquid sample and reagent quantities, increase sensitivity as well as speed of analysis and facilitate portable systems via the integration of components such as pumps, valves, mixers, separation units, reactors and detectors. READ MORE