Search for dissertations about: "Minimal inhibitory concentration"

Found 5 swedish dissertations containing the words Minimal inhibitory concentration.

  1. 1. Selection of Resistance at very low Antibiotic Concentrations

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erik Gullberg; Uppsala universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibiotic resistance; Selection; Antibiotic resistant bacteria; Minimal inhibitory concentration; Heavy metals; Conjugative plasmid; ESBL; Mikrobiologi; Microbiology; Biology with specialization in Microbiology; Biologi med inriktning mot mikrobiologi; Biology with specialization in Molecular Evolution; Biologi med inriktning mot molekylär evolution;

    Abstract : The extensive medical and agricultural use and misuse of antibiotics during the last 70 years has caused an enrichment of resistant pathogenic bacteria that now severely threatens our capacity to efficiently treat bacterial infections. While is has been known for a long time that high concentrations of antibiotics can select for resistant mutants, less is known about the lower limit at which antibiotics can be selective and enrich for resistant bacteria. READ MORE

  2. 2. Biological and Pharmacological Factor that Influence the Selection of Antibiotic Resistance

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Ingegerd Gustafsson; Uppsala universitet.; [2003]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Microbiology; Human microflora; antibiotic resistance; selection; mutation frequency; biological fitness; pharmacokinetics; pharmacodynamics; β-lactam antibiotics; suboptimal dosing regimen; Mikrobiologi; NATURAL SCIENCES Biology Organism biology Microbiology; NATURVETENSKAP Biologi Organismbiologi Mikrobiologi; Klinisk bakteriologi; Clinical Bacteriology;

    Abstract : Antibiotic treatment causes an ecological disturbance on the human microflora. Four commensal bacteria: E. coli, enterococci, a-streptococci and coagulase-negative staphylococci, from patients with extensive, high antibiotic usage were investigated with regard to resistance pattern and mutation frequency. READ MORE

  3. 3. Chlamydia pneumoniae in Aortic Valve Sclerosis and Thoracic Aortic Disease Aspects of Pathogenesis and Therapy

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Christina Nyström-Rosander; Uppsala universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Chlamydia pneumoniae; aortic valve sclerosis; trace elements; thoracic aorta; antibiotics; Polymerase Chain Reaction PCR ; electron microscopy EM ; Infektionssjukdomar; MEDICINE Microbiology; immunology; infectious diseases Infectious diseases; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Infektionssjukdomar; infektionssjukdomar; Infectious Diseases;

    Abstract : The obligate intracellular bacterium Chlamydia pneumoniae (Cp), a common human pathogen, has been associated with atherosclerotic cardiovascular disease. The aetiology of non-rheumatic aortic valve sclerosis has, however, not been clarified. READ MORE

  4. 4. Beta-Lactamase in Haemophilus ducreyi: Purification, Characterization, and Mutagenesis

    University dissertation from Pure and Applied Biochemistry, Lund University

    Author : Ratana Lawung; Lunds universitet.; Lund University.; [2001]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biokemi; Metabolism; Biochemistry; enzyme calorimeter; site-directed mutagenesis; ampicillin resistance plasmid; Haemophilus ducreyi; TEM-1 b-lactamase; metabolism; Proteins; enzymology; Proteiner; enzymologi; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Chancroid caused by Haemophilus ducreyi, has been described as a significantly predisposing factor of HIV heterosexual transmission in an endemic region of both diseases. Antibiotic resistances are extensively found in H. ducreyi and many of the resistances are due to the presence of resistance plasmids. READ MORE

  5. 5. Borrelia channel-forming proteins structure and function

    University dissertation from Umeå : Umeå University

    Author : Ignas Bunikis; Umeå universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; Lume disease; relapsing fever; BesC; drug efflux; DipA; P66; porins; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics Molecular biology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Borrelia is a Gram-negative, corkscrew-shaped bacterium transmitted by infected ticks or lice. Borreliae are subdivided into pathogens of two diseases: Lyme disease, caused mainly by B. burgdorferi, B. afzelii and B. READ MORE