Search for dissertations about: "Mohamed Mahmoud Issa"

Found 1 swedish dissertation containing the words Mohamed Mahmoud Issa.

2. 1. Linear and Branched Chitosan Oligomers as Delivery Systems for pDNA and siRNA In Vitro and In Vivo

   Author : Mohamed Mahmoud Issa; Per Artursson; Arto Urtti; Uppsala universitet; []
   Keywords : Medical sciences; Chitosan oligomers; gene delivery; gene expression; pDNA; siRNA; MEDICIN OCH VÅRD;

   Abstract : In this thesis, chitosan, a biocompatible polysaccharide that has been approved as a food additive was selected as a platform for the development of safe, efficient non-viral gene delivery systems to mammalian cells. Previously, chitosan-based gene formulations had been generally associated with high molecular weight chitosans, which were poorly characterised in terms of molecular weight distribution and degree of acetylation. READ MORE