Search for dissertations about: "Mutation model"

Showing result 1 - 5 of 317 swedish dissertations containing the words Mutation model.

2. 1. A Mutation-based Framework for Automated Testing of Timeliness

   Author : Robert Nilsson; Sten F. Andler; Michael G. Hinchey; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Automated Testing; Timeliness; Real-time systems; Time constraints; Model-based; Mutation testing; Computer science; Datalogi;

   Abstract : A problem when testing timeliness of event-triggered real-time systems is that response times depend on the execution order of concurrent tasks. Conventional testing methods ignore task interleaving and timing and thus do not help determine which execution orders need to be exercised to gain confidence in temporal correctness. READ MORE

4. 2. Mutational effects on protein structure and function

   Author : Jonas Carlsson; Persson Bengt; Uwe Sauer; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mutation; prediction; phenotypes; homology model; virtual screening; molecular dynamics; amyloid; cancer; membrane protein; Bioinformatics; Bioinformatik;

   Abstract : In this thesis several important proteins are investigated from a structural perspective. Some of the proteins are disease related while other have important but not completely characterised functions. READ MORE

5. 3. Statistical Mechanical Studies of Aqueous solutions and Biomolecular Systems

   Author : Fernando Luis Barroso Da Silva; Beräkningskemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; highly charged macromolecules; dielectric discontinuity; dissociation constant; Tanford-Kirkwood model; protein mutation; electrostatic interactions; chemical potential; titration; biomolecules; computer simulations; radial distribution function; electrolyte solutions; continuum model.; Theoretical chemistry; quantum chemistry; Teoretisk kemi; kvantkemi;

   Abstract : This thesis is concerned with theoretical studies of aqueous solutions and biomolecular systems. Part of the present work is to understand equilibrium solvent and solute properties, while the other part is to study processes that occur in these solutions. READ MORE

6. 4. Biosensor technology applied to hybridization analysis and mutation detection

   Author : Peter Nilsson; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biosensor; genosensor; surface plasmon resonance; hybridization; nucleic acids; oligonucleotide; mutation detection; mismatch discrimination; modular; Bioengineering; Bioteknik;

   Abstract : This thesis demonstrates the application of biosensor technology for molecular biology investigations, utilizing a surface plasmon resonance based optical device for mass sensitive detection of biomolecular interactions at a chipsurface. Oligonucleotide model systems were designed for analysis of the action of DNA manipulating enzymes. READ MORE

7. 5. A Multitype Branching Processes Approach to the Evolutionary Dynamics of Escape

   Author : Maria Conceicao Serra; Göteborgs universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Galton-Watson branching processes; multitype; decomposable processes; population dynamics; extinction; mutation; path to escape; waiting time to escape; Galton-Watson branching processes;

   Abstract : Evolutionary dynamics of escape is a recent development in theoretical biology. It is an attempt to predict possible patterns of population dynamics for a certain strain of viruses placed in a hostile environment. The only way to escape extinction for the virus is to find a new form better adapted to the new environment. READ MORE