Search for dissertations about: "NATURVETENSKAP Biologi Cell- och molekylärbiologi Cellbiologi"
Showing result 1 - 5 of 123 swedish dissertations containing the words NATURVETENSKAP Biologi Cell- och molekylärbiologi Cellbiologi.
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1. Effects of adenosine and acetylcholine on the lacrimal gland
Abstract : A balanced tear film is essential for a healthy ocular surface. Insufficient tear production may result in dry eye, a common disorder in the elderly population. Dry eye causes significant discomfort in the patients and may lead to visual impairment and ocular infections. READ MORE
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2. Evolutionary and Pharmacological Studies of NPY and QRFP Receptors
Abstract : The neuropeptide Y (NPY) system consists of 3-4 peptides and 4-7 receptors in vertebrates. It has powerful effects on appetite regulation and is involved in many other biological processes including blood pressure regulation, bone formation and anxiety. READ MORE
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3. High-throughput screening using multicellular tumor spheroids to reveal and exploit tumor-specific vulnerabilities
Abstract : High-throughput drug screening (HTS) in live cells is often a vital part of the preclinical anticancer drug discovery process. So far, two-dimensional (2D) monolayer cell cultures have been the most prevalent model in HTS endeavors. However, 2D cell cultures often fail to recapitulate the complex microenvironments of in vivo tumors. READ MORE
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4. Studies on the Role of Apoptosis in Kidney Diseases
Abstract : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. READ MORE
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5. Stochastic modelling and analysis of early mouse development
Abstract : The aim of this thesis is to model and describe dynamical events for biological cells using statistical and mathematical tools. The thesis includes five papers that all relate to stochastic modelling of cells. READ MORE