Search for dissertations about: "Nasal respiratory mucosa"

Showing result 1 - 5 of 25 swedish dissertations containing the words Nasal respiratory mucosa.

  2. 1. Olfactory Transfer of Analgesic Drugs After Nasal Administration

    Author : Ulrika Espefält Westin; Erik Björk; Eva Brittebo; Margareta Hammarlund-Udenaes; Paolo Colombo; Uppsala universitet; []
    Keywords : Pharmaceutics; Nasal administration; Olfactory transfer; Olfactory pathways; Central nervous system; Blood-brain barrier; Nasal respiratory mucosa; Olfactory mucosa; Olfactory bulb; Horizontal Ussing chamber; Morphine; Dihydroergotamine; Rat; Mouse; Swine; Autoradiography; Viability; Powder formulations; Galenisk farmaci;

    Abstract : Nasal administration of analgesics for achieving rapid pain relief is currently a topic of great interest. The blood-brain barrier (BBB) restricts access to the central nervous system (CNS) for several central-acting drugs, such as morphine and dihydroergotamine, which results in a substantial effect delay. READ MORE

  4. 2. Chronic Obstructive Pulmonary Disease (COPD) Epidemiological and Pan-airway Aspects

    Author : Ulf Nihlén; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Respiratory system; spirometry; nasal polyposis; nasal symptoms; prevalence; incidence; coronary heart disease; alcohol; airways; COPD; FEV1; Andningsorganen;

    Abstract : Background – Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. However, there is little information on the prevalence and particularly on the incidence of COPD. READ MORE

  5. 3. Phospholipase A2 expression in the human nasal mucosa

    Author : John Lindbom; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Phospholipase A2 (PLA2) is a superfamily of enzymes that play a key role in inflammation by releasing arachidonic acid for the synthesis of eicosanoids and lysophospholipid for the synthesis of platelet-activating factor (PAF). On the other hand, several members of the PLA2 family (VIIA, VIIB, VIIIA and VIIIB) are able to degrade PAF and are therefore potentially important anti-inflammatory enzymes. READ MORE

  6. 4. Proteome response of upper respiratory system following particle exposure

    Author : Neserin Ali; Avdelningen för arbets- och miljömedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Mass Spectrometry MS ; upper airway mucosa; Particles; Nasal Lavage Fluid;

    Abstract : .... READ MORE

  7. 5. Systems Biology Based Approaches to Identify Biomarkers in Seasonal Allergic Rhinitis

    Author : Hui Wang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucocorticoids; Seasonal allergic rhinitis; Biomarkers; Gene expression microarray analysis; Proteomics; Multivariate analysis; Pathway analysis;

    Abstract : Glucocorticoids (GC) are the most effective anti-inflammatory treatment for seasonal allergic rhinitis (SAR). However, a few patients with SAR show poor response to GC treatment. Hence, there is a clinical need to find biomarkers to predict and monitor treatment response. READ MORE