Search for dissertations about: "Neointima"

Showing result 1 - 5 of 22 swedish dissertations containing the word Neointima.

  2. 1. The inflammatory response to arterial injury

    Author : Paul Dimayuga; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; neointima; arterial injury; inflammation; Kardiovaskulära systemet;

    Abstract : Atherosclerosis as a disease is postulated to stem from a response to injury of the arterial wall by various stimuli. The inflammatory response is proposed to mediate intimal formation after injury. One pathway of cellular response to injury is through transcription factor NF-kB. READ MORE

  4. 2. Signal transduction in restenosis and myocardial protection by hyperoxia

    Author : Arno Ruusalepp; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neointima; inflammation; NF-kappaB; preconditioning; MAPK; nitric oxide;

    Abstract : Ischemic heart disease is a major cause of morbidity and mortality in the western world. Revascularization of ischemic myocardium is essential for cell survival, and is performed by thrombolysis, percutaneous transluminal coronary angioplasty (PTCA) and by coronary artery bypass grafting. READ MORE

  5. 3. Development of intimal hyperplasia in transplant arteriosclerosis

    Author : Piotr Religa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Vascular disease is the main cause of disability and mortality in the western world and the major limiting factor for long- term survival of transplanted organs. Occlusive vascular lesions lead to ischemia and structural changes in organs and in transplant arteriosclerosis and restenosis after endovascular procedures, narrowing of the vessel lumen is partly due to intimal hyperplasia caused by smooth muscle cells (SMCs). READ MORE

  6. 4. Developmental origin and molecular regulation of vascular smooth muscle cells

    Author : Per Wasteson; Göteborgs universitet; []
    Keywords : smooth muscle cell; aorta; cell origin; lateral plate mesoderm; paraxial mesoderm; lipoma preferred partner; serum response factor; neointimal hyperplasia; angiotensin II; platelet-derived growth factor-B;

    Abstract : Several pathologies of the vascular system have been suggested to be dependent on the smooth muscle cells (SMCs) that build up the vessel wall. Aortic SMCs have been proposed to derive from lateral plate mesoderm. READ MORE

  7. 5. Vascular repair mechanisms : experimental, physiological and clinical studies

    Author : Anton Razuvajev; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular disease is the leading cause of global mortality and physical disability mainly due to the complications of atherothrombosis such as myocardial infarction or stroke. Surgical treatment directed to prevent this conditions is limited by the extensive healing response, intimal hyperplasia. READ MORE