Search for dissertations about: "Neoplasms pathology"

Showing result 1 - 5 of 7 swedish dissertations containing the words Neoplasms pathology.

  2. 1. Regulation of Angiogenesis

    Author : Helena Larsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; angiogenesis; anti-angiogenesis; endostatin; latent antithrombin; prelatent antithrombin; Crk; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Angiogenesis is the formation of new blood vessels from pre-existing ones. New blood vessel formation is fundamental in processes such as reproduction, embryonic development and wound healing. Growth of neoplasms is accompanied by increased angiogenesis. This thesis describes cellular and molecular mechanisms of importance for angiogenesis. READ MORE

  4. 2. Human Bone Marrow Microenvironment in Health and Disease

    Author : Sandro Bräunig; Avdelningen för molekylär hematologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic microenvironment; Imaging; Myeloproliferative neoplasms; Spatial relationships; acute lymphoblastic leukaemia ALL ; Fibrosis; Mesenchymal stromal cell; Single cell RNA sequencing;

    Abstract : Hematopoietic stem cells (HSCs) are safeguarded from various threats such as stress, injury, or radiationwithin specialized microenvironments or niches within the bone marrow. In this thesis, we investigatedvarious facets of the bone marrow (BM) microenvironment and its critical role in hematopoiesis andrelated disorders. READ MORE

  5. 3. Male Subfertility and Prostate Cancer Risk: Epidemiological and Genetic Studies

    Author : Yasir Ruhayel; Malmö Molekylärgenetisk reproduktionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cytoplasmic and nuclear; Receptors; Prostatic neoplasms; genetic; Polymorphism; male; Infertility; Hypogonadism; Genetic association studies; Case–control studies; Androgens;

    Abstract : Androgen action plays a pivotal role in male reproductive tract physiology and pathology. The androgen receptor (AR) gene harbors two codon repeat tracts: the CAG and GGN repeats, encoding corresponding amino acid sequences of variable length; the polyglutamine and polyglycine stretches, respectively. READ MORE

  6. 4. CT colonography. Technique, diagnostic accuracy and patient acceptance

    Author : Maria H Svensson (Reutersköld); Göteborgs universitet; []
    Keywords : Colon; Rectum; Computed tomography; Three-dimensional imaging; Colorectal neoplasms; Colonic polyps; Colonoscopy; Acceptance testing; Incidental findings; Diagnostic accuracy;

    Abstract : The aim was to evaluate diagnostic potential, technical performance, and patient acceptance of CT colonography when used for detection of colorectal polyps and cancer in symptomatic patients with a high risk of colorectal neoplasia.Methods: After bowel preparation, 111 symptomatic patients underwent CT colonography followed by conventional colonoscopy. READ MORE

  7. 5. Clinical implementation of novel diagnostic biomarkers for epithelial ovarian cancer - Can we improve diagnosis?

    Author : Maria Lycke; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ovarian neoplasms; EOC; Diagnosis; protein biomarkers; HE4; CA125; Algorithms; RMI; ROMA; NGS; rare mutations; liquid biopsies; screening;

    Abstract : Background: Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer. The 5-year survival is about 30%, a consequence of failure to establish early diagnosis due to unspecific symptoms. READ MORE