Search for dissertations about: "Neuromuscular Agents"

Showing result 1 - 5 of 10 swedish dissertations containing the words Neuromuscular Agents.

  2. 1. Nicotinic transmission and drugs in anesthesia : neuromuscular blocking agents and propofol : consequences for carotid body function

    Author : Malin Jonsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Carotid body; chemoreceptors; neuromuscular blocking agents; propofol; acetylcholine; nicotinic acetylcholine receptors;

    Abstract : The carotid body is the global oxygen sensor of the human body. Acute hypoxia elicits instant hyperventilation mediated from the carotid body type 1 cells, where nicotinic transmission is a key component in oxygen sensing and signalling. READ MORE

  4. 2. Pharyngeal function, airway protection and anesthetic agents

    Author : Eva Sundman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Aspiration; postoperative pulmonary complications; hypoxia; sedation.;

    Abstract : Anesthesia related complications occur most frequently in the immediate postoperative period. The three most common conditions associated with such events are ventilatory failure, airway obstruction and aspiration. The pharynx is essential for respiration and protection of the upper airway. READ MORE

  5. 3. Molecular And Cellular Networks in Critical Illness Associated Muscle Weakness : Skeletal Muscle Proteostasis in the Intensive Care Unit

    Author : Varuna Chaminda Banduseela; Lars Larsson; Gustavo Nader; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chaperones; autophagy; intensive care unit; heat shock proteins; protein synthesis; proteostasis; ER stress; gene expression; sepsis; neuromuscular blockers; corticosteroids; immobilisation; mechanical ventilation; Molekylär cellbiologi; Molecular Cellbiology; Molekylär medicin; Molecular Medicine;

    Abstract : Critical illness associated muscle weakness and muscle dysfunction in intensive care unit (ICU) patients lead to severe morbidity and mortality as well as significant adverse effect on quality of life. Immobilization, mechanical ventilation, neuromuscular blocking agents, corticosteroids, and sepsis have been implicated as important risk factors, but the underlying molecular and cellular mechanisms remain unclear. READ MORE

  6. 4. A Muscle Perspective on the Pathophysiology of Amyotrophic Lateral Sclerosis : Differences between extraocular and limb muscles

    Author : Vahid M. Harandi; Jingxia Liu; Fatima Pedrosa Domellöf; Per Stål; Fawzi Kadi; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuromuscular junctions; Extraocular muscles; Skeletal muscle; Neurotrophic factor; Wnt; Motor neuron disease; Amyotrophic lateral sclerosis; SOD1G93A mice; molekylärbiologi; Molecular Biology;

    Abstract : Background: Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disorder. ALS has been traditionally believed to be primarily a motor neuron disease. READ MORE

  7. 5. On the interaction between a neuromuscular blocking agent and regulation of breathing during hypoxia

    Author : Nicholas Wyon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neuromuscular block; TOF ratio; vecuronium; ventilatory response; chemoreceptors; carotid body;

    Abstract : It was previously generally agreed that a mechanical train-of-four (TOF) ratio >0.70 represented an adequate recovery of respiratory function after neuromuscular blockade. Normal respiratory parameters at this level of recovery and during air breathing support this view. READ MORE