Search for dissertations about: "Non-small cell lung carcinoma"

Showing result 11 - 15 of 21 swedish dissertations containing the words Non-small cell lung carcinoma.

  2. 11. ASNA1 and cisplatin resistance : studies in C. elegans and in human tumor cells

    Author : Oskar Hemmingsson; Peter Naredi; Mef Nilbert; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ASNA1; Cisplatin; C. elegans; Drug resistance; Apoptosis; Surgery; Kirurgi; Oncology; Onkologi; Surgery; kirurgi; Oncology; onkologi; cellforskning; cell research;

    Abstract : Platinum based chemotherapy is widely used to treat cancer. Cisplatin (diamminedichloroplatinum) combination treatments provide cure for metastatic testicular cancer and prolong survival for patients suffering from ovarian, head and neck, bladder and non small cell lung cancer. READ MORE

  4. 12. Decoding the tumor microenvironment : a B-cell and macrophage perspective

    Author : Vanessa F Boura; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The immune system plays a role in many different functions in our body, and disease is no exception. Cancer is one of the biggest challenges of the twenty first century and vast efforts have been made to understand this disease. READ MORE

  5. 13. Delection mapping of human 3p in major epithelial types of cancer and fine localization of candidate tumor suppressor genes

    Author : Jian Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Tumor suppressor gene; epithelial carcinoma; human chromosome 3p;

    Abstract : Allele loss and deletion mapping using microsatellite markers and the detection of homozygous deletions represented until now the most powerful method to localize potential TSGs. Loss of heterozygosity (LOH) involving several chromosome 3p regions accompanied by chromosome 3p deletions are detected in almost 100% of renal cell carcinoma (RCC), small (SCLCs) and more than 90% of non-small (NSCLC) cell lung cancers. READ MORE

  6. 14. ROR1 – a druggable target : preclinical studies of ROR1 and combinatorial partners in malignancies

    Author : Amineh Ghaderi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer cells are masters of adaption, and their ability to sustain proliferative signaling presents a complicated challenge to cancer treatment. Therefore, novel drugs that attack key drivers of cancer cell growth are urgently needed. READ MORE

  7. 15. Analyses of the expression and function of the aspartic protease napsin

    Author : Takayuki Ueno; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Two-dimensional gel electrophoresis (2 DE) is one of the powerful tools for the expression profiling of proteins. Using 2 DE, two polypeptides which are expressed exclusively in primary lung adenocarcinomas have been described. Mass spectrometry of tryptic digests of these proteins revealed that they were identical to napsin A. READ MORE