Search for dissertations about: "Nucleic Acid"

Showing result 1 - 5 of 189 swedish dissertations containing the words Nucleic Acid.

2. 1. Nucleic acid analysis tools : Novel technologies and biomedical applications

   Author : Iván Hernández-Neuta; Mats Nilsson; Frank Bier; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nucleic acid analysis; padlock probes; selector probes; rolling circle amplification; microfluidics; single-molecule detection; digital quantification; fluorescence microscopy; mobile phone microscopy; molecular diagnostics; virology; Biochemistry; biokemi;

   Abstract : Nucleic acids are fundamental molecules of living organisms functioning essentially as the molecular information carriers of life. From how an organism is built to how it responds to external conditions, all of it, can be found in the form of nucleic acid sequences inside every single cell of every life form on earth. READ MORE

4. 2. Molecular Tools for Nucleic Acid Analysis

   Author : Deirdre O'Meara; KTH; []
   Keywords : nucleic acid capture; modular probes; biosensor; bio-magnetic separation; hepatitis C; sequencing; pyrosequencing; mutation detection; HIV-1; drug resistance; SNP; allele-specific extension; apyrase; genotyping.;

   Abstract : Nucleic acid technology has assumed an essential role invarious areas ofin vitrodiagnostics ranging from infectious diseasediagnosis to human genetics. An important requirement of suchmolecular methods is that they achieve high sensitivity andspecificity with a fast turnaround time in a cost-effectivemanner. READ MORE

5. 3. Padlock Probe-Based Nucleic Acid Amplification Tests : Point-of-care Diagnostics of Infectious Diseases

   Author : Sibel Ciftci; Mats Nilsson; Jonas Klingström; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nucleic Acid Amplification; Isothermal Amplification Methods; Padlock Probes; Rolling Circle Amplification; Molecular Diagnostics; Infectious Disease Diagnostics; Virus; Point-of-Care; Biochemistry; biokemi;

   Abstract : Recent advancements in molecular biology and biotechnology have pushed the field of molecular diagnostics much further to benefit the society towards smart access for rapid and simplified health care. In this context, point-of-care (PoC) technologies that bring the inventions in diagnostics closer to bedside settings draw attention. READ MORE

6. 4. Nucleic Acid Based Pathogen Diagnostics

   Author : Michael S. Akhras; Pål Nyrén; Nader Pourmand; Mats Nilsson; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; pathogen diagnostics; antibiotic resistance; connector inversion probes CIPer ; human papillomavirus HPV ; genotyping; global health diagnostic forum; molecular inversion probe MIP ; neisseria gonorrhoeae; padlock probes; pyrosequencing; Biochemistry; Biokemi;

   Abstract : Pathogenic organisms are transmitted to the host organism through all possible connected pathways, and cause a myriad of diseases states. Commonly occurring curable infectious diseases still impose the greatest health impacts on a worldwide perspective. READ MORE

7. 5. Nucleic acid based therapeutic approaches

   Author : Joacim Elmén; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Nucleic acid therapy comprises several approaches based on nucleic acid as the active therapeutic component to treat human disease. Antisense and short interfering RNA (siRNA) are two gene-silencing techniques in this category. Based on nucleic acid sequence recognition both techniques inhibit gene expression. READ MORE