Search for dissertations about: "Nucleoporin"
Showing result 1 - 5 of 10 swedish dissertations containing the word Nucleoporin.
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1. Nucleoporins and Protein Transport in Drosophila
Abstract : Many biological responses rely on the selective translocation of transcriptional regulators in and out of the nucleus through nuclear pore complexes (NPC). More than one million macromolecules per minute pass through the NPC and an important challenge is to understand the coordination of nucleocytoplasmic trafficking. READ MORE
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2. The evolution of the nuclear envelope
Abstract : The nucleus is one of the defining features of eukaryotes and the question of its origin is intimately linked to the evolution of the eukaryotic cell. It is delimited by a double lipid bilayer called the nuclear envelope, which separates the nuclear interior from the cytoplasm. READ MORE
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3. Disassembly and reassembly of the nuclear pore complex
Abstract : The nuclear pore complexes (NPCs) are multiprotein communicative channels spanning the nuclear envelope. In higher eukaryotes NPCs reversibly disassemble during mitosis into distinct nucleoporin subcomplexes. Some cell types (e.g. READ MORE
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4. Functional study of Nucleoporins Nup88 and Nup214 during Drosophila Development
Abstract : More than a million macromolecules per minute pass through the nuclear envelope of a eukaryotic cell. An important challenge is to understand how the NPC coordinate efficiently the bi-directional trafficking necessary for the basal cellular activities and the rapid translocation of regulatory proteins in response to signaling. READ MORE
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5. Molecular and ultrastructural analysis of Tpr, a nuclear pore complex-attached coiled-coil protein
Abstract : Anchored in the nuclear envelope, nuclear pore complexes (NPCs) are large multiprotein complexes which serve as the gateway for nucleocytoplasmic transport. In vertebrates, a 267kDa protein termed Tpr has been localized to the nucleoplasmic side of the NPCs. The function of Tpr has remained largely elusive. READ MORE