Search for dissertations about: "Nucleotide sugars"

Showing result 1 - 5 of 9 swedish dissertations containing the words Nucleotide sugars.

  2. 1. Nucleotide-Dependent Processes in the Thylakoid Lumen of Plant Chloroplasts

    Author : Björn Lundin; Cornelia Spetea Wiklund; Zach Adam; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; plant; chloroplast; thylakoid; nucleotide; PSII; PsbO; Biology; Biologi;

    Abstract : Plants, algae and photosynthetic bacteria are able to harvest the sunlight and use its energy to transform water and carbon dioxide to carbohydrate molecules and oxygen, both important to sustain life on Earth. This process is called photosynthesis and is the route by which almost all energy enters the biosphere. READ MORE

  4. 2. UDP-sugar metabolizing pyrophosphorylases in plants : formation of precursors for essential glycosylation-reactions

    Author : Daniel Decker; Leszek A. Kleczkowski; Henrik Vibe Schelle; Umeå universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chemical library screening; Cell wall synthesis; Glycosylation; Nucleotide sugars; Oligomerization; Protein structure; Reverse chemical genetics; Sugar activation; UDP-sugar synthesis; biokemisk farmakologi; biochemical pharmacology; biokemi; Biochemistry; biology; biologi; molekylärbiologi; Molecular Biology;

    Abstract : UDP-sugar metabolizing pyrophosphorylases provide the primary mechanism for de novo synthesis of UDP-sugars, which can then be used for myriads of glycosyltranferase reactions, producing cell wall carbohydrates, sucrose, glycoproteins and glycolipids, as well as many other glycosylated compounds. The pyrophosphorylases can be divided into three families: UDP-Glc pyrophosphorylase (UGPase), UDP-sugar pyrophosphorylase (USPase) and UDP-N-acety lglucosamine pyrophosphorylase (UAGPase), which can be discriminated both by differences in accepted substrate range and amino acid sequences. READ MORE

  5. 3. Determining Ligand- and Lipid- Interactions of SLC Transporters

    Author : Yurie Chatzikyriakidou; David Drew; Robert Fredriksson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Solute carrier transporter; nucleotide-sugar transporter; SLC35; sodium proton exchanger; SLC9B2; thermal stability assay; membrane transport; Synaptic vesicle protein 2; Biochemistry; biokemi;

    Abstract : Solute carrier transporters (SLCs) mediate the inter- and intra- cellular trafficking of a plethora of substrates and are essential to cell homeostasis. Despite their importance to human physiology and their potential as therapeutic targets, many SLCs are considered orphans as the physiological substrate has not been experimentally determined. READ MORE

  6. 4. Establishing the mechanistic basis of sugar transport

    Author : Abdul Aziz Qureshi; David Drew; Magnus Wolf-Watz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane transport; transport energetics; nucleotide-sugar transporters; glucose transporters; malaria; cancer; Biochemistry; biokemi;

    Abstract : Sugar is a vital molecule required for cell viability and homeostasis. Sugar is important for metabolic energy, energy storage, signaling, structure and osmolyte regulation. Transport of sugar represents an important physiological process. READ MORE

  7. 5. Structural and biochemical insights into biosynthesis and degradation of N-glycans

    Author : Tom Reichenbach; Christina Divne; David Drew; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; N-glycan; biosynthesis; degradation; glycosyltransferase; glycoside hydrolase; biofuel; enzyme; membrane protein; Bioteknologi; Biotechnology;

    Abstract : Carbohydrates are a primary energy source for all living organisms, but importantly, they also participate in a number of life-sustaining biological processes, e.g. cell signaling and cell-wall synthesis. The first part of the thesis examines glycosyltransferases that play a crucial role in the biosynthesis of N-glycans. READ MORE