Search for dissertations about: "Olfactory transfer"
Showing result 1 - 5 of 8 swedish dissertations containing the words Olfactory transfer.
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1. Olfactory Transfer of Analgesic Drugs After Nasal Administration
Abstract : Nasal administration of analgesics for achieving rapid pain relief is currently a topic of great interest. The blood-brain barrier (BBB) restricts access to the central nervous system (CNS) for several central-acting drugs, such as morphine and dihydroergotamine, which results in a substantial effect delay. READ MORE
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2. Nasal administration of compounds active in the central nervous system : Exploring the olfactory system
Abstract : The nasal administration of drugs offers advantages over administration by intravenous injection. Drugs can be rapidly absorbed through the nasal mucosa, resulting in a rapid onset of action, and also avoiding degradation in the gastrointestinal tract and first-pass metabolism in the liver. READ MORE
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3. Models for the Transfer of Drugs from the Nasal Cavity to the Central Nervous System
Abstract : The blood-brain barrier restricts the access of many compounds, including therapeutic agents, to the brain. Several human studies indicate that nasal administration of hydrophilic compounds, such as peptides, can bypass the blood-brain barrier. The aims of this thesis were to develop and refine models for this direct nose-to-brain transfer. READ MORE
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4. Drugs in the olfactory pathways: bioactivation, toxicity and transfer to the brain
Abstract : .... READ MORE
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5. Novel measure of olfactory bulb function in health and disease
Abstract : Present neuroimaging techniques are capable of recording the neural activity from all over the brain but the olfactory bulb (OB). The OB is the first olfactory processing stage of the central nervous system and the site of insult in several neurological disorders, particularly Parkinson’s disease (PD). READ MORE