Search for dissertations about: "Oligosaccharides chemistry"
Showing result 1 - 5 of 48 swedish dissertations containing the words Oligosaccharides chemistry.
-
1. Studies of oligosaccharides and carbon-13 enriched bacterial polysaccharides using NMR spectroscopy and computer simulations
Abstract : The conformation and dynamics of the trisaccharide methyl β-D-Glcp-(1--> 2)[β-D-Glcp-(1 --> 3)] α-D-Manp and its constituent disaccharides methyl β-D-Glcp-(1 --> 2) α-D-Manp and methyl β-D-Glcp-(1 --> 3) α-D-Manp have been studied using computer simulations and NMR spectroscopy. The computer simulations applied were Metropolis Monte Carlo simulations employing the HSEA force field and Langevin dynamics simulations using the PARM22 and CHEAT95 force fileds. READ MORE
-
2. Conformations of Flexible Oligosaccharides : Molecular Simulations and NMR spectroscopy
Abstract : The conformational preferences of several oligosaccharides are investigated herein using a combination of NMR spectroscopy and molecular dynamics (MD) simulations, focusing on the torsion angles associated with the glycosidic linkages.Strategies for obtaining usable J-HMBC spectra for carbons with an adjacent 13C label are described. READ MORE
-
3. Probing Dynamics of Oligosaccharides by Interference Phenomena in NMR Relaxation
Abstract : Oligosaccharides (carbohydrates) are a large class of biological molecules that are important as energy sources in the human body and have enormously varied biological functions. It is generally believed that biological activities of carbohydrates are related to their internal dynamics. READ MORE
-
4. Conformational Dynamics of Carbohydrates Studied by NMR Spectroscopy and Molecular Simulations
Abstract : Carbohydrates play important roles in biological processes. Their function is closely related to their conformation. In this thesis, conformational studies of carbohydrates by NMR spectroscopy and molecular dynamics computer simulations are described. READ MORE
-
5. Synthesis of Conformationally Restricted Oligosaccharides
Abstract : Gangliosides are sialic acid-containing glycosphingolipids that often are present in increased amounts on tumor cells. Since the gangliosides are hydroxy-acids, they can form lactones. The lactones have been suspected to be more immunogenic than the open forms, but are in practise poor immunogens due to their ease of hydrolysis. READ MORE