Search for dissertations about: "Osteoporosis: drug therapy"

Found 5 swedish dissertations containing the words Osteoporosis: drug therapy.

  1. 1. Following the mevalonate pathway to bone heal alley

    Author : Björn Skoglund; Lars Nordsletten; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Bone screws; coated materials; biocompatible; chemistry; diphosphonates; pharmacology; Equipment failure analysis methods; Femoral fractures; drug therapy; fracture fixation; instrumentation; Fracture fixation; fracture healing; drug effects; simvastatin; tibial fractures; physiopathologyial fractures; surgery; Pharmaceutical chemistry; Farmaceutisk kemi; Other veterinary medicine; Övrig veterinärmedicin;

    Abstract : The mevalonate pathway is an important biosynthetic pathway, found in all cells of virtually all known pro- as well as eukaryotic organisms. This thesis is an investigation into the use of two drugs, originally developed for different applications, but both affecting the mevalonate pathway, in to models of fracture repair. READ MORE

  2. 2. Hip fracture prevention by screening and intervention of elderly women in primary health care

    Author : Daniel M Albertsson; Göteborgs universitet; []
    Keywords : hip fracture; fractures; mortality; women; aged; risk factors; risk assessment; accidental falls; questionnaires; accident prevention; house calls; exercise therapy; drug therapy; bone density; BMD; absorptiometry; intervention studies; primary health care; Sweden;

    Abstract : Hip fracture prevention by screening and intervention of elderly women in Primary Health Care Daniel Albertsson Background – One in four Swedish women suffers a hip fracture (HF). In order to identify high-risk women we developed clinical 4-item scores as the FRAMO (Fracture and Mortality) Index, evaluated heel bone mineral density (BMD) and undertook interventions to improve mobility, reduce falls and HF. READ MORE

  3. 3. Drug use in institutionalized and home-dwelling elderly persons

    Author : Ylva Haasum; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The overall aim of this thesis is to investigate drug use in institutionalized and home- dwelling elderly, with a special focus on dementia. The major findings from the separate studies are summarized below. READ MORE

  4. 4. Unequal drug treatment : age and educational differences among older adults

    Author : Jonas W Wastesson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The overall aim of this thesis is to investigate whether drug treatment is unequally distributed among older adults on the basis of age and socioeconomic position. All studies in this thesis are based on nationwide register data from the Swedish Prescribed Drug Register (SPDR) record-linked to other registers in Sweden. READ MORE

  5. 5. Pharmacological Modulation of Skeletal Homeostasis

    Author : Niklas U. Andersson; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Farmakologi; toxicology; farmakognosi; farmaci; toxikologi; pharmacy; pharmacognosy; Pharmacological sciences; peripheral quantitative computed tomography.; dual energy X-ray absorptiomenty; estrogen; parathyroid hormone; gastrectomy; alendronate; ovariectomy; Bone;

    Abstract : Both ovariectomy (OVX) and gastrectomy (GX) cause osteopenia in several animal species including humans. While the effect of OVX has been ascribed to estrogen deficiency, the underlying mechanism behind GX-induced osteopenia is poorly understood. READ MORE