Search for dissertations about: "P. Jones"
Showing result 1 - 5 of 12 swedish dissertations containing the words P. Jones.
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1. Targeting Infectious Disease : Structural and functional studies of proteins from two RNA viruses and Mycobacterium tuberculosis
Abstract : The recent emergence of a number of new viral diseases as well as the re-emergence of tuberculosis (TB), indicate an urgent need for new drugs against viral and bacterial infections.Coronavirus nsp1 has been shown to induce suppression of host gene expression and interfere with host immune response. READ MORE
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2. Metabolic engineering strategies to increase n-butanol production from cyanobacteria
Abstract : The development of sustainable replacements for fossil fuels has been spurred by concerns over global warming effects. Biofuels are typically produced through fermentation of edible crops, or forest or agricultural residues requiring cost-intensive pretreatment. READ MORE
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3. Exploring the Biopsychosocial Model in Irritable Bowel Syndrome : with emphasis on stress, comorbidities and fatigue
Abstract : BackgroundIrritable bowel syndrome (IBS) is a common, chronic, relapsing, and sometimes disabling, symptombased disorder of gut brain interactions. It has got a female predominance and occurs in all ages, with a slight decrease among elderly. READ MORE
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4. Evolution of the subcortical circuits controlling goal-directed behaviour
Abstract : The aim of the work presented in this thesis was to reconstruct the minimal neural hardware that vertebrates use for goal-directed behaviour. By studying lamprey, one of the phylogenetically oldest vertebrates, we were able to identify the neural circuitry that has been conserved since jawed and jawless vertebrates diverged over 560 million years ago. READ MORE
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5. Structural and Biochemical Characterizations of Three Potential Drug Targets from Pathogens
Abstract : As antibiotic resistance of various pathogens emerged globally, the need for new effective drugs with novel modes of action became urgent. In this thesis, we focus on infectious diseases, e.g. READ MORE