Search for dissertations about: "P13"

Showing result 1 - 5 of 28 swedish dissertations containing the word P13.

  2. 1. Structure and Function of the Borrelia burgdorferi Porins, P13 and P66

    Author : Mari Bonde; Sven Bergström; Melissa Caimano; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; P13; P66; porin; protein complex; dissemination; osmotic stress;

    Abstract : Borrelia burgdorferi is an elongated and helically shaped bacterium that is the causal agent of the tick-borne illness Lyme disease. The disease manifests with initial flu-like symptoms and, in many cases, the appearance of a skin rash called erythema migrans at the site of the tick bite. READ MORE

  4. 2. Porins of Borrelia burgdorferi

    Author : Marija Pinne; Sven Bergström; Magnus Höök; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lyme disease; P13; paralog; P66; channel-forming activity; porin; Medical microbiology; Medicinsk mikrobiologi;

    Abstract : Borrelia burgdorferi is a pathogenic spirochete which cycles between its arthropod vector and vertebrate host. If transmitted to humans, B. burgdorferi causes Lyme disease, an infection which can impair different organs, such as the skin, joints, nervous system and heart. READ MORE

  5. 3. Molecular mechanisms underlying the glucose-dependent transcription of the insulin and glucokinase genes in the pancreatic beta-cell

    Author : Tilo Moede; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Insulin is of vital importance in the maintenance of the glucose homeostasis in mammals. This necessitates a tight regulation of both insulin release and biosynthesis. READ MORE

  6. 4. Responses to Tumour initiating factors and Regulation of Normal and Malignant Haematopoiesis

    Author : Eva Diffner; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The haematopoietic stem cell (HSC) resides within a specific environment enabling it to retain its self-renewal capacity or quiescent state. It is proposed that the HSC niche is hypoxic, a milieu within which the HSC is protected from intrinsic and extrinsic stimuli. READ MORE

  7. 5. Prognostic molecular markers of childhood leukemia

    Author : Fredrika Gauffin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acute lymphoblastic leukemia; dic 9; 20 ; dried blood spots; Guthrie card; RNA; PTEN; SHP1; VEGF; VEGFR-1; VEGFR-2; immuhistochemistry; tissue micro array;

    Abstract : During the last decades there has been a dramatic increase in survival rates for childhood leukemia, resulting today in an overall survival close to 90 % for children with acute lymphoblastic leukemia (ALL). This accomplishment is largely due to treatment protocols based on careful risk group assessment guiding the type and intensity of the anti-leukemic treatment. READ MORE