Search for dissertations about: "PEGylation"

Showing result 1 - 5 of 11 swedish dissertations containing the word PEGylation.

2. 1. Adenovirus-mediated Gene Therapy of Prostate Cancer

   Author : Angelika Danielsson; Mangus Essand; Thomas H. Tötterman; Gunnel Hallden; Uppsala universitet; []
   Keywords : adenovirus; adenoviral vector; oncolytic virus; gene therapy; prostate cancer; PEGylation; HDAC inhibitor; whole blood model; whole blood neutralization assay; MEDICINE; MEDICIN; Klinisk immunologi; Clinical Immunology; Molekylär genetik; Molecular Genetics;

   Abstract : Adenovirus-mediated gene therapy is a potential complement to standard cancer treatments. Advantages are that vectors can be used to target tumors and that replicating viruses lead to increased therapeutic dosage. READ MORE

4. 2. Isolation and chemical modification of arabinoxylan and galactoglucomannan

   Author : Linda Härdelin; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Tg; Films; Material properties; Isolation; Etherification; Modification; PEGylation; Hemicellulose;

   Abstract : Today’s society is based on the use of fossil fuels, where oil is used as transportation fuel and as raw material in the petrochemical industry. Efforts are made to increase the use of bio-based materials, since oil is a non-renewable source and a greenhouse gas contributor. READ MORE

5. 3. Polymeric Nanoparticles as Carriers for Antimicrobial Peptides : Factors Affecting Peptide and Membrane Interactions

   Author : Randi Nordström; Martin Malmsten; Per Hansson; Helena Bysell; Erica Wanless; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antimicrobial peptide; microgel; degradable; nanogel; drug delivery; PEGylation; secondary structure; model membrane; lipid bilayer; neutron reflectometry; ellipsometry; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

   Abstract : As resistance towards conventional antibiotics is becoming more pronounced, cationic antimicrobial peptides (AMPs) have received considerable attention as possible therapeutic alternatives. Thousands of potent AMPs occur in humans, animals, plants and fungi as a natural part of the immune system. READ MORE

6. 4. Drug Eluting Hydrogels : Design, Synthesis and Evaluation

   Author : Lage Ahrenstedt; Deon Bezuidenhout; Michael Malkoch; University of Cape Town; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drug delivery; PEGylation; Rapamycin; Dexamethasone; Controlled release; Hydrogels; Slow release;

   Abstract : Hydrogels have successfully proved themselves useful for drug delivery applications and several delivery routes have been developed over the years. The particular interest in this work was to design, synthesise and evaluate in situ forming drug eluting hydrogels, which have the potential to ameliorate the healing of cardiovascular diseases. READ MORE

7. 5. Microrheology of Concentrated Protein Solutions

   Author : Tommy Garting; Fysikalisk kemi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Microrheology; Dynamic Light Scattering; Protein; Pegylation; Viscosity;

   Abstract : The behavior of concentrated protein solutions is of general high interest due to implications in, for example, biological systems and medical applications. It is necessary to investigate the rheological properties of such systems to understand how parameters, such as stability, are affected by the high concentrations. READ MORE