Search for dissertations about: "PFIDH"

Found 1 swedish dissertation containing the word PFIDH.

2. 1. Structure determination, thermal stability and catalytic mechanism of hyperthermostable isocitrate dehydrogenases

   Author : Mikael Karlström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : X-ray crystallography; isocitrate dehydrogenase; thermostability; catalytic mechanism;

   Abstract : In this thesis, studies on the enzyme isocitrate dehydrogenase (IDH) from the hyperthermophiles Aeropyrum pernix (ApIDH), Thermotoga maritima (TmIDH), Archaeoglobus fulgidus (AfIDH) and Pyrococcus furiosus (PfIDH) are presented. The aim of the described work was to contribute to the understanding of protein thermostability and to study the catalytic mechanism. READ MORE