Search for dissertations about: "PLASMODIUM FALCIPARUM GENETIC DIVERSITY"
Showing result 1 - 5 of 9 swedish dissertations containing the words PLASMODIUM FALCIPARUM GENETIC DIVERSITY.
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1. Diversity and dynamics of Plasmodium falciparum malaria
Abstract : The epidemiology of genetic diversity of malaria parasites in relation to clinical parameters, acquisition of immunity and malaria transmission has implications for the development and evaluation of control measures such as vaccines and drugs. The diversity and dynamics of Plasmodium falciparum infections were therefore studied with a polymerase chain reaction (PCR)-based genotyping method targeting three highly polymorphic genes coding for potential vaccine candidate antigens: the two merozoite surface proteins msp1 block 2 and msp2 and the glutamine rich protein (glurp). READ MORE
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2. Genetic diversity of Plasmodium falciparum infections : influence on protective malaria immunity
Abstract : Detailed knowledge of the interaction between the human host and the antigenic and genetic diversity of Plasmodium falciparum infections is a prerequisite for understanding the mechanisms underlying acquisition of immunity to malaria. This thesis assessed the diversity of P. READ MORE
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3. Dynamics of Resistant Plasmodium falciparum Parasites
Abstract : Persistence of drug resistant Plasmodium falciparum is a major problem to management and control malaria in endemic areas. The focus of this thesis was to study the dynamics of resistant P. falciparum parasites. READ MORE
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4. Genomic and transcripto variation in blood stage Plasmodium falciparum
Abstract : Malaria research has entered a postgenomic era since October 2002, when the complete genomic sequence of Plasmodium falciparum strain 3D7 was published. A massive amount of information generated by the P. falciparum genome project has facilitated the development of many novel platforms for profiling different levels of biological aspects. READ MORE
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5. Naturally acquired immunity to plasmodium falciparum malaria : antibody responses and immunological memory
Abstract : Plasmodium falciparum malaria is a significant public health concern particularly in Sub-Saharan Africa. Effective malaria vaccines will contribute significantly towards controlling the disease but their development is hampered by the incomplete understanding of immunity to malaria. READ MORE