Search for dissertations about: "PNPLA3"

Found 4 swedish dissertations containing the word PNPLA3.

  1. 1. Susceptibility to chronic liver disease

    Author : Maria Antonella Burza; Göteborgs universitet.; Gothenburg University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic liver disease; susceptibility; human genetics; NAFLD; ALD; PNPLA3;

    Abstract : The onset and the progression of chronic liver disease involve environmental and genetic factors. Hepatic stellate cells (HSCs) are important players in these processes and are the main storage site for retinol. READ MORE

  2. 2. Adipose tissue gene expression & candidate genes for obesity

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Lovisa Johansson; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; Insulin resistance; Adipose tissue; Adiponutrin; PNPLA; PPARGC1A; Gene expression; Case-control association study; Microarray; Genotyping; Population-based study;

    Abstract : Obesity results from an interaction between genetic and environmental factors and is a growing health problem associated with development of insulin resistance, type 2 diabetes and cardiovascular disease. This thesis has focused on investigating the genetic contribution in obesity and insulin resistance by both candidate and global gene approaches with focus on the adipose tissue. READ MORE

  3. 3. Impact of Host Genetic Variants on Natural History and Treatment of Hepatitis C Virus Infection

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Karolina Rembeck; Göteborgs universitet.; Gothenburg University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis C; prognostic factors;

    Abstract : Chronic hepatitis C Virus (HCV) infection causes liver disease and may progress to severe fibrosis, cirrhosis, and hepatocellular carcinoma. This thesis aimed to evaluate the impact of host genetics, i.e. READ MORE

  4. 4. Genetic variants for liver fat accumulation and circulating triglyceride levels

    University dissertation from Diabetes and cardiovascular disease - genetic epidemiology

    Author : Ivana Stojkovic; Lunds universitet.; Lund University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genetic variations; NAFLD; triglycerides; ALAT; dietary intake; type 2 diabetes; cardiovascular disease;

    Abstract : Non-alcoholic fatty liver disease (NAFLD), obesity and type 2 diabetes(T2D) are strongly associated and today their prevalence reaches epidemic proportions. NAFLD has a multi-factorial aetiology, both genetic and environmental factors are equally important. READ MORE