Search for dissertations about: "PSP"

Showing result 1 - 5 of 34 swedish dissertations containing the word PSP.

  1. 1. The diagnostic challenge of Parkinsonian syndromes. Clinical and laboratory evaluation

    Author : Björn Holmberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; MSA; PSP; autonomic tests; differential diagnosis; levodopa test; NFL; GFAP;

    Abstract : Background: The differentiation between Parkinson's disease (PD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) may be difficult, but it is important for prognostic and therapeutic purposes. The aim of this study was to evaluate the differential diagnostic capacity of laboratory tests in a population of patients fulfilling strict clinical criteria for these disorders. READ MORE

  2. 2. Health and Social Determinants Among Boys and Girls in Sweden : Focusing on Parental Background

    Author : Heidi Carlerby; Katja Gillander Gådin; Anders Knutsson; Eija Viitasara; Ina Borup; Mittuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bullying involvement; discrimination; foreign extraction; gender; WHO-HBSC; intersectional perspective; health risk behaviour; parental background; PSP; SHC; SCOS; socio-demography; mobbning; diskrimination; utländsk härkomst; genus; WHO-HBSC; intersektionalitetsperspektiv; hälsoriskbeteende; föräldrabakgrund; PSP; SHC; SCOS; sociodemografi;

    Abstract : The majority of Swedish boys and girls have good psychosomatic health. Despite that the risk of mental health problems such as nervousness, feeling low and sleeping difficulties has increased steadily in recent decades. READ MORE

  3. 3. Lysosomal network proteins as biomarkers and therapeutic targets in neurodegenerative disease

    Author : Andrea Boman; Katarina Kågedal; Samuel Svensson; Alan Sabirsh; Per Svenningsson; Oskar Hansson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cerebrospinal fluid CSF ; biomarkers; therapeutic targets; neurodegeneration; Alzheimer’s disease AD ; Parkinson’s disease PD ; Corticobasal degeneration CBD ; Progressive supraneuclear palsy PSP ; Lysosomes; Endosomes; Autophagy; LAMP-2; Lysozyme;

    Abstract : The pre-symptomatic stage of neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) occurs several decades before the clinical onset. Changes in the lysosomal network, i.e. the autophagosomal, endosomal and lysosomal vesicular system, are among the first alterations observed. READ MORE

  4. 4. Glial cell line-derived neurotrophic factor : expression patterns, neuronal transport, regulation, effects, and receptor dependence

    Author : Andreas C Tomac; Karolinska Institutet; Karolinska Institutet; []
    Keywords : glial cell line-derived neurotrophic factor GDNF ; neurturin NTN ; persephin PSP ; c Ret proto oncogene Ret ; GPI-linked receptors for the GDNF ligand family GFRas ; transforming growth factor-B TGFB ; Parkinson s disease PD ; dopaminergic DA neurons;

    Abstract : Background: The mammalian nervous system depends upon trophic proteins for survival, growth and adult maintenance. These trophic factors have also been considered as potential therapeutic agents for treating human neurodegenerative disorders. READ MORE

  5. 5. Magnetic resonance imaging techniques for diagnostics in Parkinson's disease and atypical parkinsonism

    Author : Henrik Sjöström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Parkinson’s disease (PD) is a neurodegenerative disease characterized by rigidity, hypokinesia, tremor and postural instability. PD is a clinical diagnosis based on neurological examination, patient history and treatment response. READ MORE