Search for dissertations about: "PVR"

Showing result 1 - 5 of 20 swedish dissertations containing the word PVR.

2. 1. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes

   Author : Alireza Labani Motlagh; Lucia Mincheva-Nilsson; Ola Winqvist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; EOC; HGSC; exosomes; NKG2D; MICA B; ULBP; DNAM-1; PVR; nectin-2; lncRNAs; immune suppression; anti-tumor immunity; NK-cell cytotoxicity; cytokines; Th1; Th2; T regulatory response; inflammation; tumor microenvironment;

   Abstract : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. READ MORE

4. 2. Regulation of hematopoiesis in the freshwater crayfish, Pacifastacus leniusculus : role of transglutaminase

   Author : Kingkamon Junkunlo; Irene Söderhäll; Kenneth Söderhäll; Chadanat Noonin; Mats W Johansson; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Ast1; clotting protein; crayfish; hematopoiesis; PVF PVR; ROS; transglutaminase; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

   Abstract : The freshwater crayfish, Pacifastacus leniusculus, has been used as a model for studying hematopoiesis or blood cell production or hematopoiesis and immunity. The work of this thesis aims to investigate the impact of factors such as ROS signaling, Ast1, and the PVF/PVR signaling pathway in controlling stem cell behavior during hematopoiesis and specifically the role of the crosslinking enzyme transglutaminase (TGase) in regulation of hematopoiesis. READ MORE

5. 3. In the hands of ohm : hemodynamic aspects in pulmonary hypertension

   Author : Erik Tossavainen; Per Lindqvist; Michael Henein; Stefan Söderberg; Peter Eriksson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kardiologi; Cardiology;

   Abstract : Congestive heart failure (CHF) is one of the most challenging diseases in terms of health care demand and mortality, in the western world. Despite major breakthroughs in the fields of diagnosis and treatment over the three last decades, the management of CHF still remains challenging. READ MORE

6. 4. Endothelial function during ischemia-reperfusion and effects of inhalation of nitric oxide

   Author : Lars Lindberg; Anestesiologi och intensivvård; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemiluminescence; capnography; monitoring; inhalation; mechanical ventilation; pulmonary hypertension; nitric oxide; EDRF; endothelium-derived relaxation factor; endothelium; organ preservation; Lung; lung transplantation; electrochemical fuel cell; Anaesthesiology; intensive care; Anestesiologi; intensivvård;

   Abstract : The vascular endothelium is an important regulatory organ in circulatory physiology and plays a central role in the response to acute inflammation and ischemia/reperfusion. Activation and dysfunction of the pulmonary vascular endothelium are closely related to clinical findings of pulmonary dysfunction. READ MORE

7. 5. Pulmonary hypertension. Clinical and pathophysiological studies

   Author : Nedim Selimovic; Göteborgs universitet; []
   Keywords : Pulmonary hypertension; Echocardiography; Right heart catheterisation; Pulmonary vascular resistance; Pulmonary function tests; Lung transplantation; Mortality on the waiting list; Vascular remodelling; Growth substances; Inflammation; Endothelin;

   Abstract : Pulmonary hypertension (PH) is a common abnormality, most often associated with various cardiopulmonary diseases. Pulmonary arterial hypertension (PAH) is a devastating pulmonary vascular disease characterised by the proliferation of endothelial, smooth-muscle cells and fibroblasts. READ MORE