Search for dissertations about: "Patrick Leclerc"

Found 1 swedish dissertation containing the words Patrick Leclerc.

2. 1. Characterization of the PGE2 pathway in arthritis and inflammation : mPGES-1 as a therapeutic target

   Author : Patrick Leclerc; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The inducible prostaglandin (PG) E2 pathway is defined by the concerted activities of the enzymes cyclooxygenase (COX)-2 and microsomal prostaglandin E synthase (mPGES)-1 in producing PGE2. PGE2 has pro-inflammatory and immunomodulatory functions and is involved in an array of diseases with an autoimmune and chronic inflammatory component, including rheumatoid arthritis (RA). READ MORE