Search for dissertations about: "Patrik Nygren"

Found 4 swedish dissertations containing the words Patrik Nygren.

  2. 1. De Novo Design and Characterization of Surface Binding Peptides - Steps toward Functional Surfaces

    Author : Patrik Nygren; Bengt-Harald Jonsson; Klas Broo; Linda Andersson; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Peptide; design; nanoparticle; CD; Amino acid; Organic chemistry; Organisk kemi;

    Abstract : The ability to create surfaces with well-defined chemical properties is a major research field. One possibility to do this is to design peptides that bind with a specific secondary structure to silica nanoparticles. READ MORE

  4. 2. Structural and Functional Studies of De Novo Designed Peptides at Surfaces

    Author : Patrik Nygren; Bo Liedberg; Thomas Ederth; Martin Malmsten; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biofouling; vesicles; nanoparticles; peptide; peptide design; circular dichroism; Physical chemistry; Fysikalisk kemi;

    Abstract : The work presented in this thesis deals with the structural and functional properties of peptides at surfaces. The interaction of peptides with surfaces is an ever so common occurrence in our every day life, from the bug squashed on the windshield of our car to the barnacle on our boat, and from the blood plasma used in the hospital to the proteins in our cells. READ MORE

  5. 3. Single-chain antibody construction and functional mapping of the monoclonal antibody TS1 : Its interaction with the antigen and the anti-idiotype

    Author : Patrik Holm; Birgitta Sundström; Per-Åke Nygren; Karlstads universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chemistry; Kemi; Chemistry; Kemi; Biomedicin; Biomedical Laboratory Science;

    Abstract : The aims of this study are to synthesize and produce a single-chain antibody (scFv) of the anti-cytokeratin 8 monoclonal IgG antibody TS1 and to functionally map amino acid residues important for the interaction with its antigen and the anti-idiotypic antibody TS1. The TS1 antibody has been shown to be effective in binding cytokeratin 8 (CK8) expressed in tumors in vivo and is proposed to be useful in immunotargeting and/or immunotherapy. READ MORE

  6. 4. Change Detection of the Unexpected : Enhancing change detection of the unexpected in a complex and high risk context – guiding visual attention in a digital display environment

    Author : Ulrik Spak; Else Nygren; Patrik Sörqvist; Uppsala universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; awareness; change blindness; change detection; command and control; display; feedback; human-computer interaction; inattentional blindness; monitoring; surveillance; visual cue; Människa-dator interaktion; Human-Computer Interaction; Ledningsvetenskap;

    Abstract : Change detection of objects and events in our visual surroundings is sometimes severely difficult, especially if these changes are unexpected. Such failures in change detection may cause huge malicious outcomes in contexts characterized by high levels of complexity and risk. READ MORE