Search for dissertations about: "Pharmaceutical and related technologies"

Showing result 1 - 5 of 10 swedish dissertations containing the words Pharmaceutical and related technologies.

  2. 1. Modelling of Drug Release from Reservoir and Matrix Formulations - Multiple Unit Dosage Forms and Swelling and Dissolving Matrix Systems

    Author : Per Borgquist; Avdelningen för kemiteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; swelling; XEDS; Chemical technology and engineering; Kemiteknik och kemisk teknologi; Polymer technology; biopolymers; Polymerteknik; Pharmaceutical and related technologies; Läkemedelsteknik och relaterad teknik; simulation; single pellet; single-unit release; SEM; reservoir system; poly ethylene oxide ; film-coated; matrix; mathematical model; diffusion; pellet shape; controlled release; polymer dissolution; modelling; ethyl cellulose; Coating; multiple-unit release;

    Abstract : In this work, mathematical models have been developed describing drug release from film-coated reservoir systems as well as drug release and polymer dissolution from swelling and dissolving polymer tablets. The model derivation of both systems is based on a mechanistic approach. The model describing drug release from reservoir systems, i.e. READ MORE

  4. 2. From Starch to Starch Microspheres. Formation of an Ordered Structure during Processing

    Author : Lidia Elfstrand; Livsmedelsteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Teknik; Pharmaceutical and related technologies; Läkemedelsteknik och relaterad teknik; crystallization; Technological sciences; starch microspheres; protein delivery;

    Abstract : Starch microsphere is a dosage form suitable for the encapsulation of protein drugs. The starch microspheres investigated in this thesis are intended for release of the drug in a pre-designed way, or in controlled manner. READ MORE

  5. 3. Microwave measurement techniques for industrial process monitoring and quality control

    Author : Johan Nohlert; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; powder; matched filter; fluidised bed; parameter estimation; cavity resonator; signal detection; finite element method; microwave measurement;

    Abstract : Process monitoring and quality control by sensor measurements are essential for the automatisation and optimisation of many industrial manufacturing processes. This thesis is concerned with microwave sensing, which is a measurement modality with potential to improve the in-line sensing capabilities in several industries. READ MORE

  6. 4. Spray drying of particles intended for inhalation - Investigation of significant process variables and product characteristics, with focus on degradation and solid state properties

    Author : Kristina Mosén; Avdelningen för kemiteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Läkemedelsteknik och relaterad teknik; Pharmaceutical and related technologies; carbohydrate; insulin; process conditions; crystallinity; degradation; particle size; spray drying; inhalation;

    Abstract : The interest in spray drying for production of inhalable particles has grown considerably since the late 1980s. However, which process variables that control degradation and the solid state properties have not been subject to extensive research. This thesis deals with how important characteristics of inhalation particles can be controlled, i.e. READ MORE

  7. 5. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels

    Author : Amro Hanora; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Downstream processing; macroporous; Biologically active compounds; Biotechnology; Läkemedelsteknik och relaterad teknik; Pharmaceutical and related technologies; Polymerteknik; biopolymers; Biokemisk teknik; Polymer technology; Makromolekylär kemi; Biochemical technology; Affinity chromatography; Ion exchange chromatography; Expanded bed adsorption chromatography.; Macromolecular chemistry; High through put screening; lactica acids; Endotoxin; Plasmid DNA; Cryogel columns; Bioteknik;

    Abstract : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. READ MORE