Search for dissertations about: "Phospholipid bilayer"

Showing result 1 - 5 of 23 swedish dissertations containing the words Phospholipid bilayer.

  1. 1. Interaction Between Antimicrobial Peptides and Phospholipid Membranes Effects of Peptide Length and Composition

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lovisa Ringstad; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adsorption; antibacterial; antimicrobial peptide; bilayer; ellipsometry; electrochemistry; electrostatic interactions; hydrophobicity; liposome; membrane; monolayer; phospholipid; secondary structure; supported bilayer.; PHARMACY; FARMACI; farmaceutisk fysikalisk kemi; Pharmaceutical Physical Chemistry;

    Abstract : Due to increasing problems with bacterial resistance development, there is a growing need for identifying new types of antibiotics. Antimicrobial peptides constitute an interesting group of substances for this purpose, since they are believed to act mainly by disrupting the bacterial membrane, which is a fast and non-specific mechanism. READ MORE

  2. 2. Antimicrobial Peptide Interactions with Phospholipid Membranes Effects of Peptide and Lipid Composition on Membrane Adsorption and Disruption

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Adam A Strömstedt; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antimicrobial; peptide; adsorption; liposome; membrane; melittin; cholesterol; tryptophan; phospholipid; bilayer; PHARMACY; FARMACI; farmaceutisk fysikalisk kemi; Pharmaceutical Physical Chemistry;

    Abstract : The interactions between antimicrobial peptides and phospholipid membranes were investigated, in terms of lipid headgroup variations and the role of cholesterol, as well as peptide composition and structure. Also strategies for increasing proteolytic stability were evaluated. READ MORE

  3. 3. Drug Partitioning into Natural and Artificial Membranes Data Applicable in Predictions of Drug Absorption

    University dissertation from Uppsala : Institutionen för naturvetenskaplig biokemi

    Author : Caroline Engvall; Uppsala universitet.; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Bilayer disk; Cholesterol; Drug partitioning; Drugs; Electrostatic effects; Immobilized liposome chromatography; Liposome; Membrane protein; Model membrane; Oligonucleotide-liposome complex; Phospholipid; Phospholipid bilayer; Proteoliposome; Surfactant; Biokemi; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi;

    Abstract : When drug molecules are passively absorbed through the cell membrane in the small intestine, the first key step is partitioning of the drug into the membrane. Partition data can therefore be used to predict drug absorption. READ MORE

  4. 4. Partitioning of Drugs and Lignin Precursor Models into Artificial Membranes

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Elisabet Boija; Uppsala universitet.; [2006]
    Keywords : Biochemistry; Bilayer disk; Capillary electrophoresis; Detergent; Drug; Electrostatic interaction; Hydrophobic interaction; Immobilized liposome chromatography; Lignin; Lignin precursor model; Liposome; Membrane model; Octanol water partitioning; Partitioning; Phospholipid; Phospholipid bilayer; Sterol; Biokemi;

    Abstract : The main aim of this thesis was to characterize membrane-solute interactions using artificial membranes in immobilized liposome chromatography or capillary electrophoresis. The partitioning of a solute into a cell membrane is an essential step in diffusion across the membrane. READ MORE

  5. 5. Supported phospholipid bilayer-based surface modifications for controlling cells at surfaces

    University dissertation from Chalmers University of Technology

    Author : Dorota Dahlborg; Chalmers tekniska högskola.; Chalmers University of Technology.; Chalmers tekniska högskola.; [2004]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fysik; Physics; supported phospholipid bilayer; cell-surface interaction; IKVAV; surface functionalization; peptide; neural cells; stem cells; cell attachment; cell differentiation; QCM-D;

    Abstract : .... READ MORE