Search for dissertations about: "Platelet derived growth factor receptor"
Showing result 1 - 5 of 96 swedish dissertations containing the words Platelet derived growth factor receptor.
-
1. Functions of platelet-derived growth factor-A during organogenesis
Abstract : The formation of organs during embryonic development is calledorganogenesis. This process is regulated by the genes residing in the genome. READ MORE
-
2. Platelet-derived growth factor-induced signal transduction
Abstract : Platelet-derived growth factor (PDGF), a potent mitogen for mesenchymal cells, elicits its effects by binding to cell surface tyrosine kinase receptors, denoted α- and β-receptors. This thesis describes the mechanism of interaction between stimulated PDGF receptors and various intracellular molecules. READ MORE
-
3. Regulation of the platelet-derived growth factor β-receptor
Abstract : Growth factors are important signalling molecules, regulating cell growth, as well as cell movement, differentiation and apoptosis. They bind to specific receptors on the cell surface causing activation of the receptors. Activated receptors then attract adaptor molecules that brings the signal further into the cell. READ MORE
-
4. Tissue Factor Biological Functions : Coagulation Activity in Microparticles and Signaling with Focus On Migration and Apoptosis
Abstract : Background: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein known as the main initiator of blood coagulation. TF is over-expressed on many malignant cells and apart from increasing the risk of thrombosis, the presence of TF/FVIIa also promotes the progression of cancer and metastasis by intracellular signaling. READ MORE
-
5. Transcriptional Regulation of the Platelet-Derived Growth Factor beta-receptor
Abstract : The Platelet Derived-Growth Factor (PDGF) receptors and ligands are expressed in cells of predominantly mesenchymal origin. Binding of the ligands to the receptors stimulates cell proliferation and other cellular responses such as differentiation and cell movement. READ MORE