Search for dissertations about: "Precursor"
Showing result 16 - 20 of 787 swedish dissertations containing the word Precursor.
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16. Studies of amyloid precursor protein trafficking and processing
Abstract : Alzheimer’s disease (AD) is the most common form of neurodegenerative disease that slowly impairs memory and thinking abilities. Abnormal accumulation and aggregation of amyloid β peptides (Aβ), derived from proteolytic cleavage of the amyloid precursor protein (APP), is thought to be one of the critical triggers in the pathogenesis. READ MORE
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17. Amyloid precursor protein : cellular studies and animal models
Abstract : Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterised by a number of neuropathological features, including extracellular deposits composed primarily of amyloid-β (Aβ) peptides. Aβ is derived from proteolysis of the amyloid precursor protein (APP) by consecutive action of β and γ-secretases. READ MORE
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18. Human neural precursor cells in spinal cord repair
Abstract : Traumatic spinal cord injury (SCI) often results in substantial neural cell death, axonal degeneration and demyelination, accompanied by loss of sensory and motor functions. Cell therapy may have neuroprotective effects, substitute for lost neural cells, promote regeneration and enhance remyelination in the lesioned spinal cord. READ MORE
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19. DNA precursor biosynthesis-allosteric regulation and medical applications
Abstract : Ribonucleotide reductase (RNR) is a key enzyme for de novo dNTP biosynthesis. We have studied nucleotide-dependent oligomerization of the allosterically regulated mammalian RNR using a mass spectrometry–related technique called Gas-phase Electrophoretic Mobility Macromolecule Analysis (GEMMA). READ MORE
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20. Interactions between mouse CNS cells : microglia and neural precursor cells
Abstract : The mammalian central nervous system (CNS) contains a variety of cells, all specialized to perform different functions. Most numerous are the three types of glia cells, whose basic role is to support the signaling units of the CNS, the neurons. READ MORE