Search for dissertations about: "Precursor"
Showing result 6 - 10 of 787 swedish dissertations containing the word Precursor.
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6. Physiological roles of amyloid precursor protein in vivo - zebrafish as a model
Abstract : Amyloid-beta precursor protein (APP) is an evolutionarily conserved transmembrane protein expressed in many different tissues. APP belongs to a gene family consisting of two other APP-like proteins (APLP1 and APLP2). READ MORE
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7. Assessment of precursor cell proliferation in normal and injured adult mammalian brains
Abstract : In the adult mammalian brain, new neurons are generated from neural stem cells (NSCs) which reside in the subventricular zone (SVZ) of the lateral ventricle wall and in the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus. The biology of persistent NSCs in the adult brain is poorly understood. READ MORE
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8. Physiological role of amyloid precursor protein during neural development
Abstract : Amyloid precursor protein (APP) is a type-one membrane-spanning protein with a large extracellular N-terminal domain and a small intracellular C-terminal domain. APP first gained interest due to its involvement in the pathogenesis of Alzheimer’s disease (AD). READ MORE
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9. Partitioning of Drugs and Lignin Precursor Models into Artificial Membranes
Abstract : The main aim of this thesis was to characterize membrane-solute interactions using artificial membranes in immobilized liposome chromatography or capillary electrophoresis. The partitioning of a solute into a cell membrane is an essential step in diffusion across the membrane. READ MORE
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10. DNA methylation signatures in precursor lymphoid neoplasms : with focus on clinical implications & the biology behind
Abstract : Precursor lymphoid neoplasms, namely acute lymphoblastic leukemias (ALL) and lymphoblastic lymphomas (LBL), are characterized by an aggressive proliferation of malignant progenitor B- or T-cells. To improve risk classification at diagnosis, better prognostic and treatment stratifying biomarkers are needed. READ MORE