Search for dissertations about: "Prostate cancer cell methods"

Showing result 1 - 5 of 38 swedish dissertations containing the words Prostate cancer cell methods.

2. 1. Extratumoral effects of highly aggressive prostate cancer

   Author : Kerstin Strömvall; Anders Bergh; Sofia Halin Bergström; Göran Landberg; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; tumor instructed normal tissue; TINT; non-malignant prostate tissue; lymph nodes; lymph node metastasis; pre-metastatic niche; tumor microenvironment; tumor macroenvironment; tumor immunoediting; Dunning rat model of prostate cancer;

   Abstract : Prostate cancer (PC) is the most common cancer in Sweden. Most patients have slow growing tumors that will not cause them any harm within their lifetime, but some have aggressive tumors and will die from their disease. READ MORE

4. 2. Metastatic spinal cord compression in prostate cancer : clinical and morphological studies

   Author : Sead Crnalic; Richard Löfvenberg; Anders Widmark; Anders Bergh; Sten Nilsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; bone metastasis; spinal cord compression; surgical treatment; survival prognosis; early diagnosis; androgen receptor; Orthopaedics; ortopedi; Pathology; patologi; Oncology; onkologi;

   Abstract : Background: Bone metastases occur in most patients with advanced hormone-refractory prostate cancer causing pain, pathologic fractures, and spinal cord compression. Few studies specifically address surgical treatment of metastatic spinal cord compression (MSCC) in prostate cancer. READ MORE

5. 3. Mechanisms behind growth of castration-resistant prostate cancer bone metastases

   Author : Emma Jernberg; Pernilla Wikström; Jack Schalken; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; castration-resistance; bone metastases; androgen receptor; intratumoral steroidogenesis; androgen receptor splice variants; androgen receptor amplification; patologi; Pathology;

   Abstract : Background: The first-line treatment for patients with advanced prostate cancer (PC) is androgen deprivation therapy. This therapy is initially effective, but after some time tumors relapse, predominantly within the bone, and are then termed castration-resistant prostate cancer (CRPC). READ MORE

6. 4. Prospective studies of hormonal and life-style related factors and risk of cancer

   Author : Sara Wirén; Pär Stattin; Håkan Jonsson; Tanja Stocks; Alicja Wolk; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; epidemiology; androgens; risk factors; fatherhood status; dizygotic twins; height; cohort; case-control; prospective; Cancer Epidemiology; cancerepidemiologi;

   Abstract : Background: Androgens are important in prostate cancer development but how circulating levels of androgens affect risk of prostate cancer of different aggressiveness is not clear. Being childless has been associated with a lower risk of prostate cancer, but it is not clear if this association is causal or a result of residual confounding. READ MORE

7. 5. Examining the prostate stroma and vasculature : importance and potential as targets for therapy

   Author : Anna Johansson; Anders Bergh; Arne Östman; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; castration therapy; vasculature; stroma; the angiopoietins; the PDGF-receptors; mast cells; Pathology; Patologi;

   Abstract : Background. Recent studies in cancer research have focused on the reciprocal interaction between cancer cells and their microenvironment. Tumour growth is angiogenesis dependent and the rate of angiogenesis correlates with a poor prognosis in many different cancers. READ MORE