Search for dissertations about: "Prostate-Specific Antigen analysis"

Showing result 1 - 5 of 29 swedish dissertations containing the words Prostate-Specific Antigen analysis.

  2. 1. Metabolism of free and complexed prostate - specific antigen and their utility for diagnosis and prognosis of prostate cancer

    Author : Thomas Björk; Malmö Urologisk cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benign prostatic hyperplasia; alpha-1-antichymotrypsin; PSA; prostate cancer; prostate-specific antigen; Urology; nephrology; Urologi; nefrologi;

    Abstract : Prostate-specific antigen (PSA) is a glycoprotein produced by the prostate gland. It occurs in several molecular forms in the blood and assays have been developed to measure free PSA and PSA in complex with alpha-1-antichymotrypsin (PSA-ACT). READ MORE

  4. 2. Structure, evolution and expression of glandular kallikrein genes

    Author : Yvonne Ceder; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ileum.; Clinical chemistry; Klinisk kemi; Tissue distribution; Androgen responsive element; Ortholog; Evolution; Prostate cancer; Glandular kallikreins; Prostate-specific antigen;

    Abstract : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. READ MORE

  5. 3. Biochemical Studies of Semenogelins with Emphasis on Zinc-Binding Properties

    Author : Magnus Jonsson; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sexualitet; sexuality; Obstetrik; gynekologi; andrologi; reproduction; andrology; gynaecology; Obstetrics; Klinisk kemi; Clinical chemistry; gel-forming proteins; surface plasmon resonance; prostate-specific antigen; protein C inhibitor; seminal plasma; zinc; semen; semenogelin; reproduktion;

    Abstract : Semenogelins I and II (SgI and SgII) are homologous and rapidly evolving proteins that have a repetitive primary structure and are synthesized mainly in the seminal vesicles. Upon ejaculation, a gelatinous coagulum is formed when the semenogelin-rich secretion from the seminal vesicles is mixed with the prostate secretion, which contains high concentrations of zinc(II) and proteases. READ MORE

  6. 4. Genetic, environmental and life-style effects on androgen receptor function

    Author : Christel Björk; Malmö Molekylärgenetisk reproduktionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reproductive function; smoking; 4 .4-DDE; persistent organic pollutants; prostate cancer; Androgen receptor; prostate specific antigen; CAG polymorphism; TCDD; aryl hydrocarbon receptor; CB-153;

    Abstract : Androgens regulate male reproductive function and their effects are mediated through the androgen receptor (AR). The AR gene contains a polymorphic CAG repeat, encoding a stretch of glutamines, affecting the transcriptional activity of the AR. READ MORE

  7. 5. Early diagnosis and treatment of prostate cancer : observational studies in the National Prostate Cancer Register of Sweden and the Västerbotten Intervention Project

    Author : Benny Holmström; Pär Stattin; Håkan Jonsson; Mattias Johansson; Gunnar Aus; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; prostate-specific antigen; single nucleotide polymorphism; Urology and andrology; Urologi och andrologi; Urology; kirurgi; särskilt urologi;

    Abstract : Prostate-specific antigen (PSA) testing has caused a steep increase in the incidence of prostate cancer, especially the incidence of localised low risk disease. In order to decrease the overdiagnosis accompanied by PSA testing, analysis of inherited genetic variants have been suggested as potential tools for clinical assessment of disease risk. READ MORE