Search for dissertations about: "Protein Folding"

Showing result 21 - 25 of 243 swedish dissertations containing the words Protein Folding.

  2. 21. Effects of Macromolecular Crowding on Protein Folding : - in-vitro equilibrium and kinetic studies on selected model systems

    Author : Alexander Christiansen; Pernilla Wittung-Stafshede; Thomas Kiefhaber; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein Folding; macromolecular crowding; excluded volume; spectroscopy; stopped-flow; biokemi; Biochemistry;

    Abstract : Protein folding is the process during which an extended and unstructured polypeptide converts to its compact folded structure that is most often the functional state. The process has been characterized extensively in dilute buffer in-vitro during the last decades but the actual biological place for this process is the inside of living cells. READ MORE

  4. 22. Structural Transitions in Helical Peptides : The Influence of Water – Implications for Molecular Recognition and Protein Folding

    Author : Martin Lignell; Hans-Christian Becker; Kaare Teilum; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein dynamics; protein folding; molten globule; time-resolved fluorescence spectroscopy; CD spectroscopy; molecular recognition; structure-function paradigm; Chemical physics; Kemisk fysik; Physical Chemistry; Fysikalisk kemi;

    Abstract : Fluctuations in protein structure are vital to function. This contrasts the dominating structure-function paradigm, which connects the well-defined three-dimensional protein structure to its function. However, catalysis is observed in disordered enzymes, which lack a defined structure. READ MORE

  5. 23. Post-synaptic Density Disc Large Zo-1 (PDZ) Domains : From Folding and Binding to Drug Targeting

    Author : Celestine Chi; Per Jemth; Maria Selmer; Sarah Linse; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; protein-protein interaction; protein folding; and drug design; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Abstract : Understanding how proteins fold and bind is interesting since these processes are central to most biological activity. Protein folding and protein-protein interaction are by themselves very complex but using a good and robust system to study them could ease some of the hurdles. READ MORE

  6. 24. Protein folding, stability and recognition

    Author : Jianxin Duan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Protein; folding; stability; recognition; molecular dynamics; protein-DNA interactions; simulation;

    Abstract : Proteins make up for most of the dry mass of a cell and they are highly involved in virtually all cellular processes. The importance of the proteins is reflected by frequent association between dysfunctional proteins and diseases. Proteins have also wide applications in industries. READ MORE

  7. 25. Protein engineering for biophysical studies of protein folding, stability and surface interactions

    Author : Martin Karlsson; Mikael Oliveberg; Linköpings universitet; []
    Keywords : Biochemistry; protein folding; NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : The subject of this thesis can be split into two parts, one that is dealing with the stability and stabilization of proteins on its own merits and a second part that deals with the protein adsorption orientation on solid surfaces and how the stability of a protein influences the behavior at a solid/liquid interface. Thus, the common denominator and focus have been on protein stability. READ MORE