Search for dissertations about: "Pulmonary vessels."

Showing result 1 - 5 of 33 swedish dissertations containing the words Pulmonary vessels..

  2. 1. Vascular remodeling in pulmonary hypertension

    Author : Ya-Ting Chang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pulmonary hypertension (PH) is a progressive obliterative vasculopathy with multifactorial etiology and high mortality rate. Endothelial dysfunction, excessive vascular remodeling, inflammation and in situ thrombosis contribute to increased vascular resistance and gradual occlusion of pulmonary vessels. READ MORE

  4. 2. In the hands of ohm : hemodynamic aspects in pulmonary hypertension

    Author : Erik Tossavainen; Per Lindqvist; Michael Henein; Stefan Söderberg; Peter Eriksson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kardiologi; Cardiology;

    Abstract : Congestive heart failure (CHF) is one of the most challenging diseases in terms of health care demand and mortality, in the western world. Despite major breakthroughs in the fields of diagnosis and treatment over the three last decades, the management of CHF still remains challenging. READ MORE

  5. 3. Endothelin in the pulmonary circulation with special reference to hypoxic pulmonary vasoconstriction

    Author : Peter Holm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : bosentan; BMS-182874; ; BQ-123; BQ-788; endothelin; endothelium; hypoxia; hypoxic pulmonary vasoconstriction; pulmonary hypertension; receptor antagonism; TBC 11251.;

    Abstract : A number of substances originating from the pulmonary endothelium have recently been found to be involved in the regulation of pulmonary vascular tone. Accumulating evidence suggests that endothelial dysfunction contributes to pulmonary hypertension, an important clinical problem often associated with hypoxemia. READ MORE

  6. 4. Hypoxic pulmonary vasoconstriction and nitric oxide

    Author : Kristina Hambraeus Jonzon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : hypoxia; pulmonary vasoconstriction; regional pulmonary bloodflow; stimulus-response; nitric oxide; blood-borne distant effects; nitric oxide synthase activity; inhaled; exhaled; non-enzymatic;

    Abstract : Hypoxia causes pulmonary vasoconstriction (HPV), improving oxygenation by redistribution of the pulmonary blood flow to better oxygenated lung regions. HPV is intrinsic to the pulmonary vascular smooth muscle cell, but can be modulated by several vasoactive substances, as for example endothelium derived nitric oxide (NO) and endothelin-1 (ET-1). READ MORE

  7. 5. Pulmonary hypertension : the role and place of PDGF

    Author : Philip Tannenberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pulmonary hypertension is a severe condition, leading to right heart dysfunction and preterm death. For pulmonary arterial hypertension (PAH), a disease group in which the primary pathology resides within the pulmonary pre-capillary vessels, several specific therapies are in clinical use, but unfortunately the prognosis is still grim. READ MORE