Search for dissertations about: "Quantitative genetics"

Showing result 1 - 5 of 137 swedish dissertations containing the words Quantitative genetics.

  2. 1. Novel Statistical Methods in Quantitative Genetics : Modeling Genetic Variance for Quantitative Trait Loci Mapping and Genomic Evaluation

    Author : Xia Shen; Örjan Carlborg; Lars Rönnegård; William Hill; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; statistical genetics; quantitative trait loci; genome-wide association study; genomic selection; genetic variance; hierarchical generalized linear model; linear mixed model; random effect; heteroscedastic effects model; variance-controlling genes; Complex Systems – Microdata Analysis;

    Abstract : This thesis develops and evaluates statistical methods for different types of genetic analyses, including quantitative trait loci (QTL) analysis, genome-wide association study (GWAS), and genomic evaluation. The main contribution of the thesis is to provide novel insights in modeling genetic variance, especially via random effects models. READ MORE

  4. 2. Chicken Genomics - Linkage and QTL mapping

    Author : Per Wahlberg; Leif Andersson; Ruedi Fries; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chicken; quantitative genetics; linkage map; QTL mapping; recombination; long-term selection; Z chromosome; selective sweep; SNP; Genetics; Genetik;

    Abstract : This thesis presents results from genetic studies conducted in the chicken (Gallus gallus). The domestication of chicken is believed to have been initiated approximately 7,000 – 9,000 years ago in Southeast Asia. READ MORE

  5. 3. Genetic Analysis of Quantitative Traits Using Domestic Animals : A Candidate Gene and Genome Scanning Approach

    Author : Hee-Bok Park; Leif Andersson; Stefan Marklund; Robert Fredricksson; Holger Luthman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Domestication; horse; pig; chicken; quantitative traits; candidate gene; genome scan; PRKAG3; MC4R; selection experiment; growth; correlated response; metabolic disorders; Quantitative Trait Loci; linkage; single nucleotide polymorphisms; Genetik; Clinical genetics; Klinisk genetik;

    Abstract : Domestication has led to genetic changes that affect quantitative traits in farm animals. Both candidate gene analysis using association tests and genome scans based on linkage analysis have been performed to understand the molecular basis underlying quantitative genetic variation in horses, pigs and chickens. READ MORE

  6. 4. Domestication Effects on the Stress Response in Chickens : Genetics, Physiology, and Behaviour

    Author : Amir Fallahshahroudi; Per Jensen; Frank Albert; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Animal domestication; stress response; gene expression; QTL; eQTL;

    Abstract : Animal domestication, the process where animals become adapted to living in proximity to humans, is associated with the alteration of multiple traits, including decreased fearfulness and stress response. With an estimated population of 50 billion, the domesticated chicken is the most populous avian species in the world. READ MORE

  7. 5. Quantitative immunochemistry in tissue sections : With special reference to urinary bladder carcinoma

    Author : Kenneth Wester; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Urinary bladder carcinoma; immunohistochemistry; quantification; image analysis; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Urinary bladder carcinoma affects about 2 000 people in Sweden every year. It is a heterogeneous disease and for adequate treatment decisions, prognostic tools are needed. Many of these are based on immunohistochemistry (MC) and hampered by poorly reproducible methodologies and subjective evaluations. READ MORE