Search for dissertations about: "RASSF1A"

Showing result 1 - 5 of 10 swedish dissertations containing the word RASSF1A.

  2. 1. Further delineation of molecular alterations in adreno-medullary tumors

    Author : Janos Geli; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Pheochromocytoma; abdominal paraganglioma; neuroblastoma; tumor suppressor gene; DNA methylation; gene expression; RIZ1; NORE1A; RASSF1A; CDKN2A;

    Abstract : Pheochromocytomas, abdominal paragangliomas and neuroblastomas are tumors of the sympathetic nervous system. Anatomically pheochromocytomas and abdominal paragangliomas arise from sympathoadrenal paraganglia, within and outside the adrenal medulla, respectively. READ MORE

  4. 2. Basic and translational studies of follicular thyroid neoplasia

    Author : Theodoros Foukakis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Follicular thyroid cancer; follicular thyroid adenoma; PAX8-PPARgamma; PPARgamma; PTEN; RAS; RASSF1A; NORE1A; TERT; quantitative RT-PCR; microarray; cancer biomarker;

    Abstract : Thyroid tumors occur frequently in the general population and although the majority represents benign follicular adenomas (FTA), thyroid cancer constitutes 1% of all malignancies worldwide. Among the differentiated cancers, three main types are recognized, including the papillary and follicular forms (PTC and FTC) that originate from the follicular thyrocytes, and the medullary carcinoma that arises from the C-cells. READ MORE

  5. 3. Behind the scenes of thyroid tumors : underlying genetic mechanisms

    Author : Jia Jing Lee; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Familial medullary thyroid cancer; follicular thyroid cancer; anaplastic thyroid cancer; CCND1; UBCH10; p16; RASSF1A; BRAF; array-CGH; tumor progression; global methylation; LINE-1; LUMA;

    Abstract : Thyroid cancer is the most frequently observed malignancy involving endocrine tissues. This group of diseases is also the major cause of death related to neoplasia of the endocrine system. Tumors in the thyroid gland are common in the general population and the majority represents benign follicular adenoma (FTA). READ MORE

  6. 4. DNA methylation and gene expression patterns in adrenal medullary tumors

    Author : Nimrod G B Kiss; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Pheochromocytomas and abdominal paragangliomas are neuroendocrine tumors of the autonomous nervous system, arising in adrenal medulla and sympathetic ganglia throughout the abdomen. These tumors originate from catecholamine-producing chromaffin cells. Neuroblastomas are common childhood tumors in the adrenal medulla and abdominal ganglia. READ MORE

  7. 5. Genetic and epigenetic mechanisms in primary hyperparathyroidism

    Author : Luqman Sulaiman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by abnormally excessive secretion of parathyroid hormone (PTH) and elevated serum calcium. PHPT patients can develop a wide range of complications affecting many body organs such as the skeleton, kidneys and heart. READ MORE