Search for dissertations about: "RNA and protein correlation"

Showing result 1 - 5 of 66 swedish dissertations containing the words RNA and protein correlation.

  2. 1. Genome-wide Characterization of RNA Expression and Processing

    Author : Ammar Zaghlool; Lars Feuk; Rickard Sandberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA sequencing; RNA splicing; RNA processing; Gene expression; Molekylär genetik; Molecular Genetics;

    Abstract : The production of fully mature protein-coding transcripts is an intricate process that involves numerous regulation steps. The complexity of these steps provides the means for multilayered control of gene expression. READ MORE

  4. 2. Global expression analysis of human cells and tissues using antibodies

    Author : Marcus Gry; Peter Nilsson; Thomas Joos; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Immunohistochemistry; protein expression; Antibody; Tissue microarray; protein quanitification; RNA and protein correlation; Bioengineering; Bioteknik;

    Abstract : To construct a complete map of the human proteome landscape is a vital part of the total understanding of the human body. Such a map could enrich the mankind to the extent that many severe diseases could be fully understood and hence could be treated with appropriate methods. READ MORE

  5. 3. The role of RNA-binding motif 3 in epithelial ovarian cancer: A biomarker discovery approach

    Author : Åsa Ehlén; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DNA integrity checkpoint; cisplatin treatment; prognostic predictive marker; RBM3; epithelial ovarian cancer; Chk1; Chk2; MCM3;

    Abstract : Epithelial ovarian cancer (EOC) is the most lethal of all gynaecological malignancies and there is an urgent need to develop new prognostic and treatment predictive biomarkers for a more efficient therapy. The discovery of the RNA-binding motif protein 3 (RBM3) as a putative cancer biomarker was based on its differential expression in various cancer forms in the Human Protein Atlas (HPA). READ MORE

  6. 4. Exploring the Molecular Dynamics of Proteins and Viruses

    Author : Daniel Larsson; David van der Spoel; Modesto Orozco; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecular dynamics; virus dynamics; capsid dissolution; satellite tobacco necrosis virus; satellite tobacco mosaic virus; virus genome structure; gas phase protein structure; water layer; micelle embedded protein; membrane protein; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Abstract : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. READ MORE

  7. 5. Prediction, Design and Determination of Protein Structures

    Author : Sebastian Rämisch; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein design; Rosetta; Fold-and-Dock; leucine rich repeat proteins; coiled-coils; molecular replacement; ab initio phasing; temperature stability; fluorescent proteins;

    Abstract : The three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. READ MORE