Search for dissertations about: "RNA-binding domains"
Showing result 1 - 5 of 19 swedish dissertations containing the words RNA-binding domains.
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1. Adapting to succeed : Post-transcriptional gene regulation in Salmonella
Abstract : Salmonella are zoonotic pathogens of worldwide economic and health importance. Both during life outside and inside the host, these pathogens are subject to continuously changing environmental conditions, such as temperature changes, acid stress, nutrient limitations, and others. READ MORE
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2. Functional studies of the Quaking gene : Focus on astroglia and neurodevelopment
Abstract : The RNA-binding protein Quaking (QKI) plays a fundamental role in post-transcriptional gene regulation during mammalian nervous system development. QKI is well known for advancing oligodendroglia differentiation and myelination, however, its functions in astrocytes and embryonic central nervous system (CNS) development remain poorly understood. READ MORE
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3. Eukaryotic Ribosome Biogenesis : Focus on the function of the assembly factor Mrd1p
Abstract : The ribosome, the protein factory of the cell, is essential for all life forms. The ribosome is a large RNA-protein machine. It is built in a complex, multi-step process that involves a large number of accessory trans-acting factors and the synthesis consumes a considerable part of the cellular energy. READ MORE
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4. A Genetic Survey of the Pathogenic Parasite Trypanosoma cruzi
Abstract : Trypanosoma cruzi, the causative agent of Chagas´ disease, is an evolutionarily ancient species with distinct biological and immunological characteristics. A fundamental understanding of the basic biology of the parasite is necessary in order to develop reliable therapeutic and prophylactic agents against T. cruzi. We have, as a part of the T. READ MORE
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5. The Modular Domain Structure of ASF/SF2: Significance for its Function as a Regulator of RNA Splicing
Abstract : ASF/SF2 is an essential splicing factor, required for constitutive splicing, and functioning as a regulator of alternative splicing. ASF/SF2 is modular in structure and contains two amino-terminal RNA binding domains (RBD1 and RBD2), and a carboxy-terminal RS domain. READ MORE