Search for dissertations about: "RNase E"

Showing result 1 - 5 of 19 swedish dissertations containing the words RNase E.

  2. 1. EF-Tu and RNase E : Essential and Functionally Connected Proteins

    Author : Disa L. Hammarlöf; Diarmaid Hughes; Måns Ehrenberg; Gerhart Wagner; Richard H Buckingham; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bacterial growth; translation; EF-Tu; RNase E; mRNA; RNA degradation; Molekylär cellbiologi; Molecular Cellbiology; Mikrobiologi; Microbiology;

    Abstract : The rate and accuracy of protein production is the main determinant of bacterial growth. Elongation Factor Tu (EF-Tu) provides the ribosome with aminoacylated tRNAs, and is central for its activity. In Salmonella enterica serovar Typhimurium, EF-Tu is encoded by the genes tufA and tufB. READ MORE

  4. 2. Blood Vessels, Biomarkers, and Broken Barriers: lnvestigations of the Brain Vasculature in Models of Neonatal Brain lnjuries

    Author : E. Axel Andersson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neonatal brain injury; hypoxia ischemia; germinal matrix haemorrhage; blood brain barrier; tight‐junctions; blood vessels;

    Abstract : Brain injury during the perinatal period can lead to lifelong impairment in cognitive and motor function, or an early death. Term neonatal encephalopathy and preterm germinal matrix haemorrhage are two conditions that can irreversibly injure the brain, but clinical tools for diagnosing and treating these pathologies are lacking. READ MORE

  5. 3. A small amoeba at the crossroads of the big RNAi world : MicroRNA biogenesis and Argonaute function in Dictyostelium discoideum

    Author : Zhen Liao; Fredrik Söderbom; Gerhart E. H. Wagner; Christina Dixelius; Kriton Kalantidis; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNAi; microRNA; Argonaute protein; miRNA biogenesis; Dictyostelium discoideum; social amoeba; Dicer; development; growth; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Small non-coding RNA (ncRNA) mediated gene silencing, known as RNAi, is a key regulatory mechanism of gene expression in eukaryotes. MicroRNAs (miRNA), one major type of small ncRNAs, are about 21nt long and bound by Argonaute proteins. READ MORE

  6. 4. Studies on endoribonuclease RNase E and its role in RNA turnover

    Author : Björn Sohlberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Gene regulation RNA processing mRNA stability endoribonucleases RNase E AUUUA-motifs Archaea;

    Abstract : RNA turnover is an important level of regulation of gene expression, by which a cell can rapidly adjust to changes in its environment. The turnover of RNA is done by an efficient but not well understood mechanism. READ MORE

  7. 5. Metal ion cooperativity in Escherichia coli RNase P RNA

    Author : Mathias Brännvall; Britt-Marie Sjöberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; RNase P; divalent metal ions; substrate interaction; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; mikrobiologi; Microbiology;

    Abstract : RNase P is an essential ribonuclease responsible for removal of the 5’ leader of tRNA precursors. Bacterial RNase P consists of an RNA subunit and a small basic protein. The catalytic activity is associated with the RNA subunit, i.e. READ MORE