Search for dissertations about: "RRBS"

Found 3 swedish dissertations containing the word RRBS.

  2. 1. Studies of epigenetic deregulation in parathyroid tumors and small intestinal neuroendocrine tumors

    Author : Elham Barazeghi; Gunnar Westin; Peter Stålberg; Per Hellman; Christofer Juhlin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; 5hmC; TET1; TET2; parathyroid tumors; SI-NET; RRBS; PTPRM;

    Abstract : Deregulation of the epigenome is associated with the initiation and progression of various types of human cancers. Here we investigated the level of 5-hydroxymethylcytosine (5hmC), expression and function of TET1 and TET2, and DNA methylation in parathyroid tumors and small intestinal neuroendocrine tumors (SI-NETs). READ MORE

  4. 2. How can an organism´s life experience affect their descendants? Insights from epigenetic and transgenerational effects of chemical exposure in zebrafish

    Author : Mélanie Blanc; Steffen Keiter; Joëlle Rüegg; Xavier Cousin; Nikolai Scherbak; Michael K. Skinner; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neurotoxicity; behavior; RNA-Seq; RRBS; TEI; permethrin; PCBs; PBDEs; coumarin 47;

    Abstract : Environmental pollution causes approx. 10% of human diseases, and some develop in the progeny because of parental exposure. Effects passed on to subsequent generations may be a consequence of genetic mutations, or of inherited changes in epigenetic patterns. READ MORE

  5. 3. Recognizing Disability and Ability in Young Autistic Children

    Author : Elisabeth Nilsson Jobs; Terje Falck-Ytter; Sven Bölte; Johan Wagemans; Uppsala universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Autism Spectrum Disorder; Early Development; CBCL 1.5 - C-TRF; SRS-2; Preschool Informants; Visual Ability; Local-Global Research; Autistic Empowerment; Psychology; Psykologi;

    Abstract : Autism Spectrum Disorder (ASD) is characterized by impairments, or disabilities, in social communication and interaction (SCI), and restricted and repetitive behaviors (RRBs), but is also associated with enhanced abilities. Early identification of disability in ASD has been a primary focus in clinical practice, while abilities associated with ASD have neither been recognized nor assessed. READ MORE