Search for dissertations about: "Retention mechanism"

Showing result 1 - 5 of 82 swedish dissertations containing the words Retention mechanism.

  2. 1. Investigations of the retention mechanisms in hydrophilic interaction chromatography

    Author : Ngoc Phuoc Dinh; Knut Irgum; Andrew J. Alpert; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HILIC; hydrophilic interaction chromatography; adsorption isotherm; water enriched layer; multivariate data analysis; retention mechanism; separation; analytisk kemi; Analytical Chemistry;

    Abstract : Hydrophilic interaction chromatography is well known as a powerful technique separation of polar and ionizable compound nowadays. However the retention mechanism of the technique is still under debate. Understanding retention mechanism would facilitate the method development using the technique and its future improvement. READ MORE

  4. 2. Study of retention mechanisms in Hydrophilic Interaction Chromatography by Nuclear Magnetic Resonance Spectroscopy

    Author : Adel Shamshir; Knut Irgum; Tobias Jonsson; Ngoc Phuoc Dinh; Torgny Fornstedt; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HILIC; hydrophilic interaction chromatography; adsorption; STD-NMR; saturation transfer difference; retention mechanism; NMRD; solid state-NMR; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis deals with investigations of the retention mechanisms in hydrophilic interaction liquid chromatography (HILIC) using nuclear magnetic resonance spectroscopy. The aims are to understand how the different types of stationary phases can influence the retention of various solutes and the adsorption abilities of solvent on stationary phases. READ MORE

  5. 3. Atherogenic lipoproteins and their interaction with proteoglycans

    Author : Christofer Flood; Göteborgs universitet; []
    Keywords : apolipoprotein B; atherosclerosis; LDL; proteoglycan; sPLA2; ; retention;

    Abstract : Atherosclerosis is a multi-factorial disease and its pathogenesis is still unclear. However, accumulating evidence during recent years has led to the concept that subendothelial retention of atherogenic lipoproteins is the initiating event in atherogenesis. READ MORE

  6. 4. Plasma-Facing Components in Tokamaks : Material Modification and Fuel Retention

    Author : Darya Ivanova; Marek Rubel; Bernard Pégourié; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; magnetic confinement fusion; plasma-facing components; plasma-facing materials; fuel inventory; erosion and deposition;

    Abstract : Fuel inventory and generation of carbon and metal dust in a tokamak are perceived to be serious safety and economy issues for the steady-state operation of a fusion reactor, e.g. ITER. READ MORE

  7. 5. Liquid Chromatography-Mass Spectrometry as a Tool for Drug Metabolite Identification in Biological Fluids : With Application to Ketobemidone

    Author : Ingela Sundström; Per Andrén; Douglas Westerlund; Monika Johansson; Uppsala universitet; []
    Keywords : Analytical chemistry; LC-MS MS; accurate mass measurement; drug metabolites; microdialysate; brain; fluorinated stationary phase; phenylboronic acid; retention mechanism; Analytisk kemi;

    Abstract : Electrospray ionization (ESI) mass spectrometry (MS) in combination with liquid chromatography (LC) is an excellent tool for the identification of drug metabolites. Utilizing this hyphenated technique in combination with proper sample pretreatment, the metabolic pathways of the analgesic drug ketobemidone were investigated in human urine and rat microdialysate from blood and brain. READ MORE