Search for dissertations about: "Risk lesions and breast cancer"

Showing result 1 - 5 of 20 swedish dissertations containing the words Risk lesions and breast cancer.

  2. 1. Breast cancer : Multifocality, heterogeneity, and related genetic signatures

    Author : Gyula Pekar; Dumanski Jan; Sapino Anna; Uppsala universitet; []
    Keywords : breast; breast cancer multifocality; molecular phenotypes; intertumoral heterogeneity; biobanking; gene copy number aberrations;

    Abstract : Breast carcinoma often exhibits a complex subgross morphology and may occupy a large volume of the breast tissue and show unifocal, multifocal or diffuse growth patterns. Expression of estrogen- and progesterone receptors, HER2 overexpression, tumor grade, and proliferative activity allows us to classify breast carcinoma into molecular subgroups (Luminal A, Luminal B, HER2-type, triple negative, and basal-like). READ MORE

  4. 2. Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer

    Author : Sofie Björner; Malmö Patologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Early diagnosis and reliable prognosis and treatment prediction of breast cancer will ultimately lead to a decreased mortality rate. This can be achieved by identification of prognostic and treatment predictive biomarkers, and by understanding the mechanisms behind early changes in the breast. READ MORE

  5. 3. Cytogenetic studies of benign breast lesions

    Author : Catarina Lundin; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; cancer risk; breast cancer; phyllodes tumor; papilloma; fibroadenoma; prophylactic mastectomies; fibrocystic lesions; Cytogenetics; chromosomes; Klinisk genetik; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

    Abstract : In the present thesis benign breast lesions of various histologies, i.e. READ MORE

  6. 4. Evaluation of image quality and diagnostic accuracy in breast tomosynthesis. Comparison with digital mammography and estimates of radiation risk

    Author : Tony Svahn; Malmö Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diagnostic accuracy; breast tomosynthesis BT ; digital mammography DM ; average glandular dose AGD ; receiver operating characteristics ROC ; risk assessment; search-model SM ; proper ROC PROPROC ;

    Abstract : Recent advances in the digital detector technology have paved the way for modalities such as two-dimensional digital mammography (DM) and three-dimensional breast tomosynthesis (BT). In this work, experimental studies were conducted to investigate the influence of reducing the average glandular dose (AGD) on detection of simulated lesions in DM and to compare the diagnostic accuracy of BT and DM. READ MORE

  7. 5. Small breast cancers : Diagnosis, prognostic factors and clinical outcome in a screening population

    Author : Lars-Gunnar Arnesson; Karl von Smitten; Linköpings universitet; []
    Keywords : Breast neoplasm; diagnostic; treatment; pathology; MEDICINE; MEDICIN;

    Abstract : Breast cancer ≤ 10 mm together with ductal in situ cancer of the breast (DCIS) today constitute more than 40% of screening detected breast malignancies. Prognostic factors, diagnosis and clinical outcome for invasive breast cancers ≤ 10 mm and local recurrence in DCIS were evaluated. READ MORE