Search for dissertations about: "Robert Kronstrand"

Showing result 1 - 5 of 6 swedish dissertations containing the words Robert Kronstrand.

  2. 1. Analytical and Toxicological Aspects of Drug Incorporation into Human Hair

    Author : Robert Kronstrand; Pascal Kintz; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The overall purpose of this thesis was to develop analytical methods for the determination of drugs and melanin content of human hair for practical use in forensic and clinical toxicology. The thesis consists of five papers, two of which are controlled single dose studies where codeine or selegiline were administered to healthy volunteers. READ MORE

  4. 2. Organelle movement in melanophores: Effects of Panax ginseng, ginsenosides and quercetin

    Author : Therese Eriksson; Rolf Andersson; Samuel Svensson; Ingemar Lundström; Robert Kronstrand; Per Hammarström; Linköpings universitet; []
    Keywords : melanophores; Panax ginseng; ginsenosides; quercetin; organell anterograde transport; endothelin-3; mitogen activated protein kinase; protein kinase C; MEDICINE; MEDICIN;

    Abstract : Panax ginseng is a traditional herb that has been used for over 2000 years to promote health and longevity. Active components of ginseng include ginsenosides, polysaccharides, flavonoids, polyacetylenes, peptides, vitamins, phenols and enzymes, of which the ginsenosides are considered to be the major bioactive constituents. READ MORE

  5. 3. Forensic Toxicological Aspects of Tramadol : Focus on Enantioselective Drug Disposition and Pharmacogenetics

    Author : Pernilla Haage; Fredrik Kugelberg; Robert Kronstrand; Espen Molden; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : One of the most difficult parts in forensic toxicology is to interpret obtained drug concentrations. Was it therapeutic, toxic or even lethal to the particular individual that the blood sample was drawn from? Concentrations of opioid drugs are especially difficult to interpret, because of large interindividual differences in innate and acquired tolerance. READ MORE

  6. 4. Oxycodone in Forensic Toxicology : Analytical Strategies and Interpretation

    Author : Gerd Jakobsson; Robert Kronstrand; Henrik Gréen; Jørgen Bo Hasselstrøm; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oxycodone; Post mortem toxicology; Drug-drug interactions; Post mortem metabolomics;

    Abstract : Oxycodone is a common finding in forensic casework and widely used as an analgetic. Oxycodone’s pharmacokinetic and pharmacodynamic properties make the interpretation of post mortem oxycodone blood concentrations complicated. READ MORE

  7. 5. Stability of zopiclone in whole blood : Studies from a forensic perspective

    Author : Gunnel Nilsson; Robert Kronstrand; Johan Ahlner; Fredrik Kugelberg; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Bio‐analytical results are influenced by in vivo factors like genetic, pharmacological and physiological conditions and in vitro factors like specimen composition, sample additives and storage conditions. The knowledge of stability of a drug and its major metabolites in biological matrices is very important in forensic cases for the interpretation of analytical results. READ MORE