Search for dissertations about: "SCID mice"
Showing result 1 - 5 of 49 swedish dissertations containing the words SCID mice.
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1. T-cell Differentiation and Immunological Homeostasis in Lymphopenic and Kappa Light Chain Deficient Mice
Abstract : T lymphocytes are primarily involved in adaptive, cell-mediated, immune reactions. In this thesis T cells were studied regarding central and peripheral differentiation and homeostatic mechanisms for maintanance of the immune repertoire.The influence by mature T cells on thymic development was studied in C. READ MORE
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2. Development and validation of a localized murine candidiasis model : The pathogenesis, chemotheraphy and defense mechanisms to Candida mastitis in the lactating mouse
Abstract : A murine model of localized candidiasis (mastitis) was developed. The model was analyzed withrespect to its discriminative abilities through investigation of the virulence properties of C.albicans mutant strains compared with the wild-type parental strain. READ MORE
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3. Immunomodulatory properties of steroid hormones
Abstract : Recent epidemiological, clinical and experimental evidence have suggested that steroid hormones play an important role in immune responses and in immune-mediated diseases. Many autoimmune diseases are treated with corticosteroids. READ MORE
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4. Humanized mice as a model to study human immunity
Abstract : Mice with human immune systems have evolved over the last three decades. Over the years, these humanized mouse models have provided us with valuable information on human immunity. Recent developments in recipient mouse strains and engraftment protocols have resulted in models with high level of de novo formation of human immune cells. READ MORE
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5. The chimeric SCID mouse in studies of the human immune system
Abstract : Several methods have been developed to transfer components of the human immune system into mice. In particular, the adoptive transfer of human Iymphoid cells or tissues into mice with severe combined immunodeficiency (SCID mice) has demonstrated the general applicability of such an approach. READ MORE