Search for dissertations about: "SCOS"
Found 4 swedish dissertations containing the word SCOS.
-
1. Health and Social Determinants Among Boys and Girls in Sweden : Focusing on Parental Background
Abstract : The majority of Swedish boys and girls have good psychosomatic health. Despite that the risk of mental health problems such as nervousness, feeling low and sleeping difficulties has increased steadily in recent decades. READ MORE
-
2. Exploring Change toward Sustainability in Established Business Models
Abstract : Sustainability outlines one of the greatest societal challenges of our time. To attain genuine sustainable development on a global level, firms must address unsustainability in their business models; that is, in what they offer to their markets, how they produce and deliver products and services, and how they collect and distribute value. READ MORE
-
3. Rational design of novel cell-penetrating peptides
Abstract : Although cell-penetrating peptides (CPPs) have been an active field of research for over 20 years there are still properties such as efficiency and stability that must be improved for CPPs to reach their full potential as delivery vectors.In this thesis two peptides were designed for non-covalent oligonucleotide delivery, in an attempt to overcome two major issues hampering wider use of CPPs, namely low stability and endosomal entrapment. READ MORE
-
4. Characterization of nucleic acid delivery with fatty acid modified cell-penetrating peptide nanoparticle formulations
Abstract : Recent advances with techniques used for manipulating gene expression have brought us to an era where various gene therapeutic approaches are becoming common therapeutic tools for many previously incurable diseases. The main factor impeding the wider translation of gene therapy is that the active pharmaceutical ingredients used for interfering with gene expression are based on nucleic acids and synthetic oligonucleotides and such molecules do not readily reach their intracellular targets due to their physicochemical properties and therefore they require delivery vectors to cross the cell membrane. READ MORE