Search for dissertations about: "SI-NET"

Showing result 1 - 5 of 10 swedish dissertations containing the word SI-NET.

  1. 1. Small Intestinal Neuroendocrine Tumors Clinical Studies, Novel Serum Biomarkers and Sensitivity to Cytotoxic and Targeted Agents

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kosmas Daskalakis; Uppsala universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SI-NET; fibrosis; locoregional surgery; liver transplantation; biomarkers; ex vivo sensitivity.;

    Abstract : Small Intestinal Neuroendocrine Tumors (SI-NETs) are indolent neoplasms with an increasing annual incidence of approximately 1/100 000 people. They are often diagnosed at a late stage, restricting treatment efficacy. READ MORE

  2. 2. Studies of epigenetic deregulation in parathyroid tumors and small intestinal neuroendocrine tumors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Elham Barazeghi; Uppsala universitet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; 5hmC; TET1; TET2; parathyroid tumors; SI-NET; RRBS; PTPRM;

    Abstract : Deregulation of the epigenome is associated with the initiation and progression of various types of human cancers. Here we investigated the level of 5-hydroxymethylcytosine (5hmC), expression and function of TET1 and TET2, and DNA methylation in parathyroid tumors and small intestinal neuroendocrine tumors (SI-NETs). READ MORE

  3. 3. Small Intestinal Neuroendocrine Tumours Genetic and Epigenetic Studies and Novel Serum Biomarkers

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Katarina Edfeldt; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kirurgi; Surgery; SI-NET; microarray; tumour suppressor gene; epigenetic; serum biomarkers;

    Abstract : Small intestinal neuroendocrine tumours (SI-NETs) are rare, hormone producing and proliferate slowly. Patients usually display metastases at time of diagnosis, the tumours are difficult to cure, and the disease course is unpredictable. READ MORE

  4. 4. Novel Circulating and Tissue Biomarkers for Small Intestine Neuroendocrine Tumors and Lung Carcinoids

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tao Cui; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small intestine neuroendocrine tumors; lung carcinoids; Ma2 autoantibodies; immunohistochemistry; olfactory receptor 51E1; blood samples; antibody suspension bead array; 小肠神经内分泌肿瘤,肺类癌,Ma2自身抗体,免疫组化,嗅觉受体蛋白51E1, 血液样本,抗体悬浮磁珠阵列; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Lungmedicin; Lung Medicine; Molecular Biology; Molekylärbiologi; Oncology; Onkologi;

    Abstract : Small intestine neuroendocrine tumors (SI-NETs) and lung carcinoids (LCs) are relatively indolent tumors, which originate from neuroendocrine (NE) cells of the diffuse NE system. Metastases can spread before diagnosis. Thus, potential cures become unavailable, which entitles new biomarker development. READ MORE

  5. 5. Small Intestinal Neuroendocrine Tumor Analyses Somatostatin Analog Effects and MicroRNA Profiling

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Su-Chen Li; Uppsala universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Small intestinal neuroendocrine tumors; Somatostatin analogs; Laser-capture microdissection; Microarray profiling and microRNA profiling; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Small intestinal neuroendocrine tumors (SI-NETs) originate from serotonin-producing enterochromaffin (EC) cells in the intestinal mucosa. Somatostatin analogs (SSAs) are mainly used to control hormonal secretion and tumor growth. However, the molecular mechanisms leading to the control of SI-NETs are unknown. READ MORE