Search for dissertations about: "SIK"

Showing result 1 - 5 of 16 swedish dissertations containing the word SIK.

  2. 1. Microscopic evaluation of hydroxypropyl potato starch granules in relation to the degrees of substitution

    Author : Hak-Ryang Kim; RISE; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; degree of substitution; hydroxypropyl potato starch; light microscopy; structural changes of starch granule; loss of birefringe; urea;

    Abstract : .... READ MORE

  4. 2. Dissolved CO2 and its growth inhibiting effect on microorganisms in MAP model systems

    Author : Jenny Löwenadler; RISE; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; modified atmosphere packaging; solubility; Pseudomonas fragi; dissolved; Yersinia enterocolitica; carbon oxide;

    Abstract : .... READ MORE

  5. 3. Diversification of TGF-β Signaling in Homeostasis and Disease

    Author : Michael Vanlandewijck; Aristidis Moustakas; Carl-Henrik Heldin; Steven Dooley; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGF-β; signaling; SIK; EMT; polarity; Notch; ALK5; p21; growth arrest; Smurf; Smad7; receptor; SNF1LK; Molecular biology; Molekylärbiologi; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : With the dawn of metazoans, the ability of cells to communicate with each other became of paramount importance in maintaining tissue homeostasis. The transforming growth factor β (TGF-β) signaling pathway, which plays important roles during embryogenesis and in the adult organism, signals via a heterodimeric receptor complex consisting of two type II and two type I receptors. READ MORE

  6. 4. Regulation of TGF-β Signaling by Post-Translational Modifications

    Author : Peter Lönn; Aristidis Moustakas; Carl-Henrik Heldin; Petra Knaus; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TGF-β; Smad; PARP-1; PARG; ALK5; SIK; signal transduction; transcription; post-translational modification; phosphorylation; ubiquitin; ADP-ribosylation; DNA-binding; receptor degradation; Cell and molecular biology; Cell- och molekylärbiologi; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Abstract : Transforming growth factor-β (TGF-β) signaling is initiated when the ligand binds to type II and type I serine/threonine kinase receptors at the cell surface. Activated TGF-β type I receptors phosphorylate R-Smads which relocate, together with co-Smads, to the cell nucleus and regulate transcription. READ MORE

  7. 5. Salt-inducible kinases in adipose tissue

    Author : Johanna Sernevi Säll; Proteinfosforylering; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; salt-inducible kinase; SIK; SIK2; fettväv; fettceller; insulinsignalering; glukosupptag; fetma; insulinresistens; salt-inducible kinase; SIK; SIK2; adipose tissue; adipocytes; insulin signalling; glucose uptake; obesity; insulin resistance;

    Abstract : Obesity, insulin resistance and type 2 diabetes (T2D) are metabolic diseases that increase rapidly in the modern society. The underlying mechanisms are complex and involve both environmental and genetic factors. Adipose tissue is an important organ for maintaining whole body energy homeostasis. READ MORE